(Q34388439)

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Can evidence from genome-wide association studies and positive natural selection surveys be used to evaluate the thrifty gene hypothesis in East Asians?

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scholarly article

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Europe PubMed Central

1 August 2017

Can evidence from genome-wide association studies and positive natural selection surveys be used to evaluate the thrifty gene hypothesis in East Asians? (English)

1 reference

Europe PubMed Central

1 August 2017

genome-wide association study

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author name string

Xuan-Han Koh

1

1 reference

Europe PubMed Central

1 August 2017

Xuanyao Liu

2

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Europe PubMed Central

1 August 2017

Yik-Ying Teo

3

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Europe PubMed Central

1 August 2017

language of work or name

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publication date

22 October 2014

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Europe PubMed Central

1 August 2017

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Europe PubMed Central

1 August 2017

9

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Europe PubMed Central

1 August 2017

10

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Europe PubMed Central

1 August 2017

e110974

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Europe PubMed Central

1 August 2017

copyright license

Creative Commons Attribution 4.0 International

22 October 2014

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April 2022 Public Data File from Crossref

copyright status

0 references

Detecting and characterizing genomic signatures of positive selection in global populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Genome-wide landscapes of human local adaptation in Asia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

1 reference

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6 July 2018

Diabetes prevalence and determinants in adults in China mainland from 2000 to 2010: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Globalization of diabetes: the role of diet, lifestyle, and genes

1 reference

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6 July 2018

Integrating common and rare genetic variation in diverse human populations

1 reference

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6 July 2018

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

1 reference

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6 July 2018

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

1 reference

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Thrift: a guide to thrifty genes, thrifty phenotypes and thrifty norms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

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Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations

1 reference

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6 July 2018

Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Evolutionary origins of the obesity epidemic: natural selection of thrifty genes or genetic drift following predation release?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Thrifty genes for obesity, an attractive but flawed idea, and an alternative perspective: the 'drifty gene' hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

A second generation human haplotype map of over 3.1 million SNPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Genome-wide association studies provide new insights into type 2 diabetes aetiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

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Evolutionary origins of insulin resistance: a behavioral switch hypothesis

1 reference

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6 July 2018

Mechanisms linking obesity to insulin resistance and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Early influences on human energy regulation: thrifty genotypes and thrifty phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

6 July 2018

Insights from the developing world: thrifty genotypes and thrifty phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206456

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Starvation in humans: evolutionary background and contemporary implications

1 reference

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Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells

1 reference

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Central nervous system control of food intake

1 reference

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6 July 2018

Insulin resistance associated with lower rates of weight gain in Pima Indians

1 reference

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6 July 2018

The double puzzle of diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110974

21 January 2018

Exploring the thrifty genotype's food-shortage assumptions: a cross-cultural comparison of ethnographic accounts of food security among foraging and agricultural societies.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110974

21 January 2018

Archaeology of NIDDM. Excavation of the "thrifty" genotype

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110974

21 January 2018

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110974

21 January 2018

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110974

21 January 2018

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110974

21 January 2018

The biological predisposition to obesity: beyond the thrifty genotype scenario

1 reference

https://pubmed.ncbi.nlm.nih.gov/25337808

12 December 2020

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10.1371/JOURNAL.PONE.0110974

1 reference

Europe PubMed Central

1 August 2017

2014PLoSO...9k0974K

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1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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