(Q34391213)

25364744

1 August 2017

title

From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action (English)

1 reference

1 August 2017

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Andreas Heinzel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Gert Mayer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Rainer Oberbauer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Arno Lukas

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bernd Mayer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

22 August 2014

1 reference

25364744

Frontiers in Cell and Developmental Biology

1 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

37

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease

7 June 2020

cites work

1 reference

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Functional molecular units for guiding biomarker panel design

6 July 2018

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Microalbuminuria: target for renoprotective therapy PRO.

6 July 2018

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Implementing precision medicine initiatives in the clinic: a new paradigm in drug development

6 July 2018

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Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus.

6 July 2018

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Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much?

6 July 2018

1 reference

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The Reactome pathway knowledgebase

6 July 2018

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Data, information, knowledge and principle: back to metabolism in KEGG

6 July 2018

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Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease

6 July 2018

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DrugBank 4.0: shedding new light on drug metabolism

6 July 2018

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Transforming growth factor-β and the progression of renal disease

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Connective tissue growth factor (CTGF) expression modulates response to high glucose

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Investigation of known estimated glomerular filtration rate loci in patients with type 2 diabetes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Serum protein profiles predict coronary artery disease in symptomatic patients referred for coronary angiography

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Connective tissue growth factor, matrix regulation, and diabetic kidney disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Systems biology: building a useful model from multiple markers and profiles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Urinary proteomics for early diagnosis in diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Perspectives on systems biology applications in diabetic kidney disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

The IntAct molecular interaction database in 2012

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Quantifying factors for the success of stratified medicine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Validity of biomarkers predicting onset or progression of nephropathy in patients with Type 2 diabetes: a systematic review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Systems biology of kidney diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Transcriptome analysis of human diabetic kidney disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Bardoxolone methyl and kidney function in CKD with type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

The productivity crisis in pharmaceutical R&D.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Database resources of the National Center for Biotechnology Information

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

HER2+ breast cancer: review of biologic relevance and optimal use of diagnostic tools

6 July 2018

1 reference

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Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer

6 July 2018

1 reference

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BioGRID: a general repository for interaction datasets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy.

6 July 2018

1 reference

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PANTHER: a library of protein families and subfamilies indexed by function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

An automated method for finding molecular complexes in large protein interaction networks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Drug target pharmacogenomics: an overview

6 July 2018

1 reference

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Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Renal function and requirement for dialysis in chronic nephropathy patients on long-term ramipril: REIN follow-up trial. Gruppo Italiano di Studi Epidemiologici in Nefrologia (GISEN). Ramipril Efficacy in Nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64).

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2014.00037

Cost effectiveness of ACE inhibitor treatment for patients with type 1 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2014.00037

Mapping of molecular pathways, biomarkers and drug targets for diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2014.00037

Combined angiotensin inhibition for the treatment of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2014.00037

Molecular models of the cardiorenal syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2014.00037

New therapies for diabetic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2014.00037

A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

The role of tubulointerstitial inflammation in the progression of chronic renal failure.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Aliskiren combined with losartan in type 2 diabetes and nephropathy

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Preparing for Precision Medicine

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207010

Evidence-based medicine versus personalized medicine: are they enemies?

9 December 2018

1 reference

12 December 2020

Molecular pathways and crosstalk characterizing the cardiorenal syndrome

1 reference

12 December 2020

Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-kappa B activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis

1 reference

12 December 2020

MCP-1 and RANTES are expressed in renal cortex of rats chronically treated with nitric oxide synthase inhibitor. Involvement in macrophage and monocyte recruitment

1 reference

12 December 2020

Identifiers

DOI

10.3389/FCELL.2014.00037

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

25364744

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25364744%20AND%20SRC:MED&resulttype=core&format=json