(Q34392423)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Angelo Torrente

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Anne Vincent

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Isabelle Bidaud

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Joel Nargeot

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Kevin Wickman

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Matteo E. Mangoni

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author name string

Jacqueline Alig

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Jana Christina Müller

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Laurine Marger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Anne Rollin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Claire Marquilly

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Stefan Dubel

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Anne Fernandez

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Anika Seniuk

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Birgit Engeland

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Jasmin Singh

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Lucile Miquerol

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Heimo Ehmke

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Thomas Eschenhagen

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Dirk Isbrandt

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

language of work or name

English

0 references

publication date

21 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

4664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4207211/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation

6 July 2018

1 reference

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SK4 Ca2+ activated K+ channel is a critical player in cardiac pacemaker derived from human embryonic stem cells.

6 July 2018

1 reference

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Modern concepts concerning the origin of the heartbeat.

6 July 2018

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HRS/ACCF expert consensus statement on pacemaker device and mode selection. Developed in partnership between the Heart Rhythm Society (HRS) and the American College of Cardiology Foundation (ACCF) and in collaboration with the Society of Thoracic Su

6 July 2018

1 reference

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Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

6 July 2018

1 reference

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Pacemaker activity and ionic currents in mouse atrioventricular node cells.

6 July 2018

1 reference

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Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Delayed afterdepolarization in intact canine sinoatrial node as a novel mechanism for atrial arrhythmia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

So Little Source, So Much Sink: Requirements for Afterdepolarizations to Propagate in Tissue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

cAMP Sensitivity of HCN Pacemaker Channels Determines Basal Heart Rate But Is Not Critical for Autonomic Rate Control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Sarcoplasmic reticulum Ca2+ pumping kinetics regulates timing of local Ca2+ releases and spontaneous beating rate of rabbit sinoatrial node pacemaker cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

The role of the funny current in pacemaker activity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Control of heart rate by cAMP sensitivity of HCN channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

What keeps us ticking: a funny current, a calcium clock, or both?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Calmodulin kinase II is required for fight or flight sinoatrial node physiology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Genesis and regulation of the heart automaticity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Tamoxifen-inducible gene deletion in the cardiac conduction system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Calcium cycling and signaling in cardiac myocytes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia

6 July 2018

1 reference

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New insights into pacemaker activity: promoting understanding of sick sinus syndrome

6 July 2018

1 reference

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Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

6 July 2018

1 reference

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Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Pacemaker channel dysfunction in a patient with sinus node disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Functional role of L-type Cav1.3 Ca2+ channels in cardiac pacemaker activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Calcium and cardiac rhythms: physiological and pathophysiological

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

The bee venom peptide tertiapin underlines the role of I(KACh) in acetylcholine-induced atrioventricular blocks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

The sinoatrial node, a heterogeneous pacemaker structure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

The evaluation and management of bradycardia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Pharmacokinetic-pharmacodynamic modeling of the effects of ivabradine, a direct sinus node inhibitor, on heart rate in healthy volunteers.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

High-level expression and detection of ion channels in Xenopus oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

A family of hyperpolarization-activated mammalian cation channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Variation in effects of Cs+, UL-FS-49, and ZD-7288 within sinoatrial node.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Mechanosensitive connective tissue: potential influence on heart rhythm

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Familial idiopathic atrial fibrillation with bradyarrhythmia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Pacemaker mechanisms in cardiac tissue.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Sick sinus syndrome in HCN1-deficient mice.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Properties of the hyperpolarization-activated current (I(f)) in isolated mouse sino-atrial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Architectural and functional asymmetry of the His-Purkinje system of the murine heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Abnormal heart rate regulation in GIRK4 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Insights into sick sinus syndrome from an inducible mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Functional roles of a Ca2+-activated K+ channel in atrioventricular nodes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

A rapidly activating delayed rectifier K+ current regulates pacemaker activity in adult mouse sinoatrial node cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Localisation and functional significance of ryanodine receptors during beta-adrenoceptor stimulation in the guinea-pig sino-atrial node

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

beta-Adrenergic stimulation modulates ryanodine receptor Ca(2+) release during diastolic depolarization to accelerate pacemaker activity in rabbit sinoatrial nodal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

HCN3 contributes to the ventricular action potential waveform in the murine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5664

Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial node

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FNCOMMS5664

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207211

Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase

27 October 2018

1 reference

12 December 2020

Conditional transgene expression in the heart

1 reference

12 December 2020

Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart

1 reference

12 December 2020

Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution

1 reference

12 December 2020

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS5664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 March 2020

ADS bibcode

2014NatCo...5.4664M

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

25144323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25144323%20AND%20SRC:MED&resulttype=core&format=json