(Q34400524)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL-mediated osteoclastogenesis (English)

1 reference

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6 February 2020

0 references

3

1 reference

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6 February 2020

author name string

Ritu Saxena

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

George Pan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Jay M McDonald

series ordinal

4

1 reference

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6 February 2020

publication date

30 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

Journal of Bone and Mineral Metabolism

6 February 2020

published in

1 reference

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6 February 2020

volume

29

1 reference

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6 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

111-122

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00774-010-0201-4

6 February 2020

exact match

0 references

cites work

Osteoblast and osteoclast differentiation in modeled microgravity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Constitutively active parathyroid hormone receptor signaling in cells in osteoblastic lineage suppresses mechanical unloading-induced bone resorption

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Cyclosporin A elicits dose-dependent biphasic effects on osteoblast differentiation and bone formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Modeled gravitational unloading triggers differentiation and apoptosis in preosteoclastic cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Microgravity: the immune response and bone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

RANKing intracellular signaling in osteoclasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the mir space station.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Calmodulin and calmodulin-dependent kinase IIalpha regulate osteoblast differentiation by controlling c-fos expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Effects of hindlimb unloading on bone histomorphometry and bone mass in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264.7 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Rotation in clinostat results in apoptosis of osteoblastic ROS 17/2.8 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Optimized suspension culture: the rotating-wall vessel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Collagen cross-link excretion during space flight and bed rest

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Bone formation and resorption biological markers in cosmonauts during and after a 180-day space flight (Euromir 95).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Human physiology in space

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Glucocorticoids and inhibition of bone formation induced by skeletal unloading

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

The effect of microgravity on bone fracture healing in rats flown on Cosmos-2044.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Physiological changes during spaceflight

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Development of a low-dose anti-resorptive drug regimen reveals synergistic suppression of bone formation when coupled with disuse

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Modeled microgravity disrupts collagen I/integrin signaling during osteoblastic differentiation of human mesenchymal stem cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Nitrogen metabolism and bone metabolism markers in healthy adults during 16 weeks of bed rest.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Bone and hormonal changes induced by skeletal unloading in the mature male rat.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Collagenase and tissue plasminogen activator production in developing rat calvariae: normal progression despite fetal exposure to microgravity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Hindlimb unloading of growing rats: a model for predicting skeletal changes during space flight

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Decreased mineralization and increased calcium release in isolated fetal mouse long bones under near weightlessness.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

Microgravity during spaceflight directly affects in vitro osteoclastogenesis and bone resorption

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000895

The physical and mechanical effects of suspension-induced osteopenia on mouse long bones

9 December 2018

1 reference

12 December 2020

Skeletal unloading in rat decreases proliferation of rat bone and marrow-derived osteoblastic cells

1 reference

12 December 2020

Effects of Bion 11 14-day space flight on monkey iliac bone

1 reference

12 December 2020

Effect of gender on bone turnover in adult rats during simulated weightlessness

1 reference

12 December 2020

Gravitational unloading induces osteoclast-like differentiation of FLG 29.1 cells

1 reference

12 December 2020

Inhibition of Bone Formation During Space Flight

1 reference

12 December 2020

Skeletal abnormalities in rats induced by simulated weightlessness

1 reference

12 December 2020

Effects of spaceflight on structural and material strength of growing bone

1 reference

12 December 2020

Alterations in calcium homeostasis and bone during actual and simulated space flight

1 reference

12 December 2020

Recovery of the rat skeleton from the adverse effects of simulated weightlessness

1 reference

12 December 2020

Effects of simulated weightlessness on bone mineral metabolism

1 reference

12 December 2020

Effects of gravitational and muscular loading on bone formation in growing rats

1 reference

12 December 2020

Effects of weightlessness on bone mass and osteoclast number in pregnant rats after a five-day spaceflight (COSMOS 1514)

1 reference

12 December 2020

The effects of simulated weightlessness on bone biomechanical and biochemical properties in the maturing rat

1 reference

12 December 2020

Adaptation of cancellous bone to aging and immobilization in the rat: a single photon absorptiometry and histomorphometry study

1 reference

12 December 2020

Histomorphometric analyses of cancellous bone from COSMOS 2044 rats

1 reference

12 December 2020

Insulin-like growth factor-I increases trabecular bone formation and osteoblastic cell proliferation in unloaded rats

1 reference

12 December 2020

Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans

1 reference

12 December 2020

Effect of mechanical unloading and reloading on periosteal bone formation and gene expression in tail-suspended rapidly growing rats

1 reference

12 December 2020

Effects of gravitational changes on the bone system in vitro and in vivo

1 reference

12 December 2020

Dose-response effects of intermittent PTH on cancellous bone in hindlimb unloaded rats

1 reference

12 December 2020

Modeled microgravity stimulates osteoclastogenesis and bone resorption by increasing osteoblast RANKL/OPG ratio

1 reference

12 December 2020

Energy and water metabolism, body composition, and hormonal changes induced by 42 days of enforced inactivity and simulated weightlessness

1 reference

12 December 2020

Trabecular bone turnover and bone marrow cell development in tail-suspended mice

1 reference

12 December 2020

Changes in the numbers of osteoclasts in newts under conditions of microgravity

1 reference

12 December 2020

10.1007/S00774-010-0201-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20589403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

20589403

1 reference