(Q34403769)

1 August 2017

The N-demethylation of imipramine correlates with the oxidation of S-mephenytoin (S/R-ratio). A population study (English)

1 reference

1 August 2017

Skjelbo E

1

1 reference

1 August 2017

Gram LF

series ordinal

2

1 reference

1 August 2017

Brøsen K

series ordinal

3

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 March 1993

1 reference

British Journal of Clinical Pharmacology

1 August 2017

1 reference

1 August 2017

35

1 reference

1 August 2017

331-334

1 reference

1 August 2017

3

1 reference

Sparteine metabolism in Canadian Caucasians

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Genetic polymorphism of S-mephenytoin hydroxylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Limitation to the use of the urinary S-/R-mephenytoin ratio in pharmacogenetic studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism--a panel study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Plasma Level Monitoring of Tricyclic Antidepressant Therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Prediction of steady-state behavior of metabolite from dosing of parent drug.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381588

Imipramine metabolites in blood of patients during therapy and after overdose

27 October 2018

1 reference

12 December 2020

Imipramine demethylation and hydroxylation: impact of the sparteine oxidation phenotype

1 reference

12 December 2020

Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism

1 reference

12 December 2020

Amitriptyline pharmacokinetics and clinical response: II. Metabolic polymorphism assessed by hydroxylation of debrisoquine and mephenytoin

1 reference

12 December 2020

Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities

1 reference

12 December 2020

S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin

1 reference

12 December 2020

The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine

1 reference

12 December 2020

Steady-state kinetics of imipramine in patients

1 reference

12 December 2020

Identifiers

PMCID

1381588

1 reference

1 August 2017

1 reference