(Q34407170)

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Identifying novel interventional strategies for psychiatric disorders: integrating genomics, 'enviromics' and gene-environment interactions in valid preclinical models.

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Europe PubMed Central

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18 March 2020

Identifying novel interventional strategies for psychiatric disorders: integrating genomics, 'enviromics' and gene-environment interactions in valid preclinical models (English)

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18 March 2020

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2

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Europe PubMed Central

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18 March 2020

Anthony J Hannan

3

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Europe PubMed Central

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18 March 2020

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Caitlin E McOmish

1

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18 March 2020

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2 July 2014

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18 March 2020

British Journal of Pharmacology

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18 March 2020

171

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24846457%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

20

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24846457%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

4719-4728

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24846457%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Decanalization mediating gene-environment interactions in schizophrenia and other psychiatric disorders with neurodevelopmental etiology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Depression and cardiovascular disease: a clinical review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Dopamine signaling in reward-related behaviors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

A Nondegenerate Code of Deleterious Variants in Mendelian Loci Contributes to Complex Disease Risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Questions about DISC1 as a genetic risk factor for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Prenatal poly(i:C) exposure and other developmental immune activation models in rodent systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Recovery in Remitted First-Episode Psychosis at 7 Years of Follow-up of an Early Dose Reduction/Discontinuation or Maintenance Treatment Strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Towards environmental construct validity in animal models of CNS disorders: optimizing translation of preclinical studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

What have we learned from recent twin studies about the etiology of neurodevelopmental disorders?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Risk architecture of schizophrenia: the role of epigenetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Synaptic scaffold evolution generated components of vertebrate cognitive complexity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Has an angel shown the way? Etiological and therapeutic implications of the PCP/NMDA model of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Decanalization, brain development and risk of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Patterns and rates of exonic de novo mutations in autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Relations among posttraumatic stress disorder, comorbid major depression, and HPA function: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

The conundrums of understanding genetic risks for autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Gene-environment interactions and construct validity in preclinical models of psychiatric disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Developmental vitamin D deficiency and risk of schizophrenia: a 10-year update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Using glutamate homeostasis as a target for treating addictive disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Research domain criteria (RDoC): toward a new classification framework for research on mental disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Functional impact of global rare copy number variation in autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

SZGR: a comprehensive schizophrenia gene resource

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Trends in risks associated with new drug development: success rates for investigational drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

A genome-wide linkage and association scan reveals novel loci for autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Candidate gene studies of ADHD: a meta-analytic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

AutDB: a gene reference resource for autism research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Gene-environment interplay between cannabis and psychosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Association between microdeletion and microduplication at 16p11.2 and autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Recurrent 16p11.2 microdeletions in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Neuroscience. Maternal effects on schizophrenia risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Strong association of de novo copy number mutations with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Enriched environments, experience-dependent plasticity and disorders of the nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Prenatal infection as a risk factor for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Genetics of affective and anxiety disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Risk for schizophrenia--broadening the concepts, pushing back the boundaries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Stress models of depression: forming genetically vulnerable strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Cellular changes in the postmortem hippocampus in major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Cross-national comparisons of the prevalences and correlates of mental disorders. WHO International Consortium in Psychiatric Epidemiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

The NMDA antagonist model for schizophrenia: promise and pitfalls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Toward a Pathophysiology of Attention-Deficit/Hyperactivint Disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Dopamine receptor supersensitivity and schizophrenia: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

The genetics of schizophrenia: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Concurrent psychiatric illness in inpatients with post-traumatic stress disorder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

6 July 2018

Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia.

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12783

21 January 2018

Epigenetic modifications induced by early enrichment are associated with changes in timing of induction of BDNF expression.

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12783

21 January 2018

Neurodevelopmental and neuropsychiatric disorders represent an interconnected molecular system

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12783

21 January 2018

Long-lasting behavioural and molecular alterations induced by early postnatal fluoxetine exposure are restored by chronic fluoxetine treatment in adult mice

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12783

21 January 2018

Cannabis use and psychosis: a longitudinal population-based study.

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12783

21 January 2018

Maternal care and DNA methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12783

21 January 2018

Reduced striatal spine size in schizophrenia: a postmortem ultrastructural study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4209939

27 October 2018

Neurobiology of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24846457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BPH.12783

1 reference

https://api.fatcat.wiki/v0/release/4q2uukpj6japtgrwwlzbrjtij4

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_4q2uukpj6japtgrwwlzbrjtij4

1 reference

https://api.fatcat.wiki/v0/release/4q2uukpj6japtgrwwlzbrjtij4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/4q2uukpj6japtgrwwlzbrjtij4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/4q2uukpj6japtgrwwlzbrjtij4

30 July 2022

based on heuristic

mapped directly with Wikidata item

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