(Q34411115)

2 August 2017

title

The RGSZ2 protein exists in a complex with mu-opioid receptors and regulates the desensitizing capacity of Gz proteins. (English)

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2 August 2017

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Javier Garzón

1

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2 August 2017

María Rodríguez-Muñoz

series ordinal

2

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2 August 2017

Almudena López-Fando

series ordinal

3

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2 August 2017

Pilar Sánchez-Blázquez

series ordinal

4

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2 August 2017

language of work or name

English

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publication date

1 September 2005

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2 August 2017

published in

Neuropsychopharmacology

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2 August 2017

volume

30

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2 August 2017

issue

9

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2 August 2017

page(s)

1632-1648

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Differential contribution of GTPase activation and effector antagonism to the inhibitory effect of RGS proteins on Gq-mediated signaling in vivo.

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Estrogen treatment increases the levels of regulator of G protein signaling-Z1 in the hypothalamic paraventricular nucleus: possible role in desensitization of 5-hydroxytryptamine1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

A truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of adenylyl cyclase and phosphoinositide phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Promotion of G alpha i3 subunit down-regulation by GIPN, a putative E3 ubiquitin ligase that interacts with RGS-GAIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Membrane-associated GAIP is a phosphoprotein and can be phosphorylated by clathrin-coated vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

In vivo modulation of G proteins and opioid receptor function by antisense oligodeoxynucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

The R7 subfamily of RGS proteins assists tachyphylaxis and acute tolerance at mu-opioid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

GX/Z Is Regulated by μ But Not δ Opioid Receptors in the Stimulation of the Low Km GTPase Activity in Mouse Periaqueductal Grey Matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Glycosylated phosducin-like protein long regulates opioid receptor function in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGSZ1 and GAIP regulate mu- but not delta-opioid receptors in mouse CNS: role in tachyphylaxis and acute tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS9 proteins facilitate acute tolerance to mu-opioid effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

The effect of protein kinase C activation on G(z)-mediated regulation of type 2 and 6 adenylyl cyclases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS10 is a selective activator of G alpha i GTPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

A core-promoter region functions bi-directionally for human opioid-receptor-like gene ORL1 and its 5'-adjacent gene GAIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

G(i1) and G(oA) differentially determine kinetic efficacies of agonists for kappa-opioid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Agonists determine the pattern of G-protein activation in mu-opioid receptor-mediated supraspinal analgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS-Rz and RGS9-2 proteins control mu-opioid receptor desensitisation in CNS: the role of activated Galphaz subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Evolution of the regulators of G-protein signaling multigene family in mouse and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

A GTPase-activating protein for the G protein Galphaz. Identification, purification, and mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Gz-mediated hormonal inhibition of cyclic AMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Systematic examination in the rat of brain sites sensitive to the direct application of morphine: observation of differential effects within the periaqueductal gray

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

Efficient functional coupling of the human D3 dopamine receptor to G(o) subtype of G proteins in SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

7 January 2021

Novel localization of a G protein, Gz-alpha, in neurons of brain and retina

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

7 January 2021

G protein alpha subunit G alpha z couples neurotransmitter receptors to ion channels in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

7 January 2021

Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

7 January 2021

Degradation of G11 alpha/Gq alpha is accelerated by agonist occupancy of alpha 1A/D, alpha 1B, and alpha 1C adrenergic receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

7 January 2021

RGS Proteins Determine Signaling Specificity of Gq-coupled Receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300726

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300726

1 reference

Dimensions Publication ID

2 August 2017

1010993518

0 references

1 reference