(Q34412157)

2 August 2017

title

Ligand Binding Sensitivity of the Extracellular Loop Two of the Cannabinoid Receptor 1. (English)

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2 August 2017

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Alexander C Bertalovitz

series ordinal

1

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2 August 2017

Kwang H Ahn

series ordinal

2

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2 August 2017

Debra A Kendall

series ordinal

3

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2 August 2017

publication date

1 November 2010

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Drug Development Research

2 August 2017

published in

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2 August 2017

volume

71

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2 August 2017

issue

7

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2 August 2017

page(s)

404-411

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Ligand-specific conformation of extracellular loop-2 in the angiotensin II type 1 receptor

2 August 2017

cites work

1 reference

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6 July 2018

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Phenylalanine 169 in the second extracellular loop of the human histamine H4 receptor is responsible for the difference in agonist binding between human and mouse H4 receptors

6 July 2018

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6 July 2018

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6 July 2018

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Systematic analysis of the entire second extracellular loop of the V(1a) vasopressin receptor: key residues, conserved throughout a G-protein-coupled receptor family, identified.

6 July 2018

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How many drug targets are there?

6 July 2018

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Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction.

6 July 2018

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The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.

6 July 2018

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An Aromatic Microdomain at the Cannabinoid CB1 Receptor Constitutes an Agonist/Inverse Agonist Binding Region

6 July 2018

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Pharmacophores for ligand recognition and activation/inactivation of the cannabinoid receptors

6 July 2018

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N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor

6 July 2018

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6 July 2018

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6 July 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

6 July 2018

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3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor

6 July 2018

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An investigation into the structural determinants of cannabinoid receptor ligand efficacy

6 July 2018

1 reference

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Ligand binding and modulation of cyclic AMP levels depend on the chemical nature of residue 192 of the human cannabinoid receptor 1.

6 July 2018

1 reference

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Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor.

6 July 2018

1 reference

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A lysine residue of the cannabinoid receptor is critical for receptor recognition by several agonists but not WIN55212-2.

6 July 2018

1 reference

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Molecular characterization of a peripheral receptor for cannabinoids

6 July 2018

1 reference

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

6 July 2018

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

6 July 2018

1 reference

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Determination and characterization of a cannabinoid receptor in rat brain

6 July 2018

1 reference

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Structure of a cannabinoid receptor and functional expression of the cloned cDNA

6 July 2018

1 reference

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Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells

6 July 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

6 July 2018

1 reference

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Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7.

6 July 2018

1 reference

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Cysteine residues in the human cannabinoid receptor: only C257 and C264 are required for a functional receptor, and steric bulk at C386 impairs antagonist SR141716A binding

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003262

Development of a 3D model for the human cannabinoid CB1 receptor.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003262

Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003262

Involvement of the carboxyl terminus of the third intracellular loop of the cannabinoid CB1 receptor in constitutive activation of Gs.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003262

Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003262

Comparative receptor binding analyses of cannabinoid agonists and antagonists.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003262

Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21170298

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/DDR.20388

1 reference

2 August 2017

1 reference

2 August 2017

1 reference