(Q34412607)

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The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15841108%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat (English)

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10 January 2020

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10 January 2020

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10 January 2020

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Athina Markou

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10 January 2020

Wolfgang Froestl

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10 January 2020

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1 November 2005

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10 January 2020

Neuropsychopharmacology

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10 January 2020

30

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10 January 2020

11

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10 January 2020

2065-2072

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10 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.npp.1300734

0 references

Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled study

1 reference

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21 January 2018

Molecular structure and physiological functions of GABA(B) receptors

1 reference

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21 January 2018

(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.

1 reference

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21 January 2018

Attenuation of d-amphetamine self-administration by baclofen in the rat: behavioral and neurochemical correlates

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21 January 2018

A potential role for GABA(B) agonists in the treatment of psychostimulant addiction

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21 January 2018

The GABA(B) antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat.

1 reference

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21 January 2018

The GABA(B) agonist CGP 44532 decreases cocaine self-administration in rats: demonstration using a progressive ratio and a discrete trials procedure.

1 reference

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21 January 2018

Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules

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21 January 2018

GABA(B) receptors: from monogamy to promiscuity

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21 January 2018

The GABA(B) receptor agonists baclofen and CGP 44532 prevent acquisition of alcohol drinking behaviour in alcohol-preferring rats

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21 January 2018

Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression.

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21 January 2018

Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat.

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21 January 2018

Non-nicotinic neuropharmacological strategies for nicotine dependence: beyond bupropion

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21 January 2018

Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents

1 reference

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21 January 2018

Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

1 reference

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21 January 2018

Reward, memory and substance abuse: functional neuronal circuits in the nucleus accumbens.

1 reference

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21 January 2018

Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine.

1 reference

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21 January 2018

The GABA(B) receptor agonist baclofen attenuates cocaine- and heroin-seeking behavior by rats

1 reference

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21 January 2018

CGP 44532, a GABAB receptor agonist, is hedonically neutral and reduces cocaine-induced enhancement of reward

1 reference

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21 January 2018

Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat

1 reference

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21 January 2018

Baclofen antagonizes intravenous self-administration of nicotine in mice and rats

1 reference

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21 January 2018

Self-stimulation response decrement patterns differentiate clonidine, baclofen and dopamine antagonists from drugs causing performance deficit.

1 reference

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21 January 2018

Dopamine release and uptake rates both decrease in the partially denervated striatum in proportion to the loss of dopamine terminals.

1 reference

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21 January 2018

Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.

1 reference

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21 January 2018

The effects of cocaine on the rate independent brain stimulation reward threshold in the mouse

1 reference

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21 January 2018

Cocaine and SKF-82958 potentiate brain stimulation reward in Swiss-Webster mice

1 reference

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21 January 2018

Agents in development for the management of cocaine abuse

1 reference

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21 January 2018

Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving

1 reference

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21 January 2018

Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens.

1 reference

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21 January 2018

Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains

1 reference

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21 January 2018

Allosteric modulation of G-protein coupled receptors.

1 reference

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21 January 2018

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

1 reference

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21 January 2018

Brain-stimulation reward, morphine-induced oral stereotypy, and sensitization: implications for abuse

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21 January 2018

Reward and detection thresholds for brain stimulation: dissociative effects of cocaine.

1 reference

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21 January 2018

Baclofen as a cocaine anti-craving medication: a preliminary clinical study.

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21 January 2018

Different sensitivity to the motor incoordinating effects of gamma-hydroxybutyric acid (GHB) and baclofen in GHB-sensitive and GHB-resistant rats

1 reference

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21 January 2018

Both GABA(B) receptor agonist and antagonists decreased brain stimulation reward in the rat.

1 reference

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21 January 2018

Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations

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21 January 2018

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

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21 January 2018

Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain

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21 January 2018

The GABA B receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat

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21 January 2018

Neurochemical correlates of brain-stimulation reward measured by ex vivo and in vivo analyses

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Involvement of GABA and cholinergic receptors in the nucleus accumbens on feedback control of somatodendritic dopamine release in the ventral tegmental area

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21 January 2018

Baclofen attenuates the reinforcing effects of cocaine in rats.

1 reference

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21 January 2018

GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent.

1 reference

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21 January 2018

Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats

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Novel approaches to the treatment of cocaine addiction

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N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

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Drug addiction: the neurobiology of behaviour gone awry

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Chronic intrathecal baclofen treatment and withdrawal: I. Changes in ankle torque and hind limb posture in normal rats

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The effects of ventral tegmental administration of GABAA, GABAB and NMDA receptor agonists on medial forebrain bundle self-stimulation.

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Localization of GABA(B) receptors in midbrain monoamine containing neurons in the rat.

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Self-stimulation and drug reward mechanisms

1 reference

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GABAB receptor stimulation decreases amphetamine-induced behavior and neuropeptide gene expression in the striatum

1 reference

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GABAA and GABAB receptor site distribution in the rat central nervous system

1 reference

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7 January 2021

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10.1038/SJ.NPP.1300734

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15841108%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15841108%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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