(Q34413669)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999931%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

title

Mechanistic studies of R67 dihydrofolate reductase. Effects of pH and an H62C mutation (English)

1 reference

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22 October 2019

4

1 reference

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22 October 2019

author name string

H Park

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999931%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

P Zhuang

series ordinal

2

1 reference

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22 October 2019

R Nichols

series ordinal

3

1 reference

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22 October 2019

language of work or name

English

0 references

publication date

1 January 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999931%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

22 October 2019

published in

1 reference

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22 October 2019

volume

272

1 reference

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22 October 2019

issue

4

1 reference

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22 October 2019

page(s)

2252-2258

1 reference

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Functional role of aspartic acid-27 in dihydrofolate reductase revealed by mutagenesis

22 October 2019

cites work

1 reference

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Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state

21 January 2018

1 reference

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Implications for enzymic catalysis from free-energy reaction coordinate profiles

21 January 2018

1 reference

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Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

21 January 2018

1 reference

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Electron redistribution on binding of a substrate to an enzyme: folate and dihydrofolate reductase

21 January 2018

1 reference

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Theoretical studies on the dihydrofolate reductase mechanism: electronic polarization of bound substrates

21 January 2018

1 reference

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Changes in the electron density of the cofactor NADPH on binding to E. coli dihydrofolate reductase

21 January 2018

1 reference

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Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate

21 January 2018

1 reference

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Classification of plasmid-encoded dihydrofolate reductases conferring trimethoprim resistance

21 January 2018

1 reference

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Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.

21 January 2018

1 reference

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A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site

21 January 2018

1 reference

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Unusual binding stoichiometries and cooperativity are observed during binary and ternary complex formation in the single active pore of R67 dihydrofolate reductase, a D2 symmetric protein

21 January 2018

1 reference

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Role of the active-site carboxylate in dihydrofolate reductase: kinetic and spectroscopic studies of the aspartate 26-->asparagine mutant of the Lactobacillus casei enzyme

21 January 2018

1 reference

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Determination by Raman spectroscopy of the pKa of N5 of dihydrofolate bound to dihydrofolate reductase: mechanistic implications

21 January 2018

1 reference

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Construction of a synthetic gene for an R-plasmid-encoded dihydrofolate reductase and studies on the role of the N-terminus in the protein.

21 January 2018

1 reference

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Construction of an altered proton donation mechanism in Escherichia coli dihydrofolate reductase

21 January 2018

1 reference

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Catalytic mechanism of the dihydrofolate reductase reaction as determined by pH studies.

21 January 2018

1 reference

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Titration of histidine 62 in R67 dihydrofolate reductase is linked to a tetramer<-->two-dimer equilibrium.

21 January 2018

1 reference

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Hydrophobic interactions via mutants of Escherichia coli dihydrofolate reductase: separation of binding and catalysis.

21 January 2018

1 reference

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Reassessment of Ellman's reagent

21 January 2018

1 reference

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Purification and properties of Escherichia coli dihydrofolate reductase

21 January 2018

1 reference

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An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of lambda repressor.

21 January 2018

1 reference

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16 Stabilization of functional proteins by introduction of multiple disulfide bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

An engineered disulfide bond in dihydrofolate reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

Universal calibration of gel permeation chromatography and determination of molecular shape in solution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

Dissociation constants for dihydrofolic acid and dihydrobiopterin and implications for mechanistic models for dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

Equilibrium Folding Studies of Tetrameric R67 Dihydrofolate Reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.4.2252

Buffers of constant ionic strength for studying pH-dependent processes

21 January 2018

1 reference

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Stereochemical modeling of disulfide bridges. Criteria for introduction into proteins by site-directed mutagenesis

21 January 2018

1 reference

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