(Q34424179)

2 August 2017

The Peutz-Jeghers kinase LKB1 suppresses polyp growth from intestinal cells of a proglucagon-expressing lineage in mice (English)

1 reference

2 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Frank Reimann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Fiona Gribble

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Guy A. Rutter

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Sagen Zac-Varghese

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paul Richards

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Sophie Sayers

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Gao Sun

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Stephen R Bloom

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

1 reference

4 September 2014

1 reference

Disease Models & Mechanisms

2 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1275-1286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

1 June 2020

copyright license

start time

18 May 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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The gut hormone glucagon-like peptide-1 produced in brain: is this physiologically relevant?

6 July 2018

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Pharmacology, physiology, and mechanisms of incretin hormone action

6 July 2018

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Novel insight into the distribution of L-cells in the rat intestinal tract

6 July 2018

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Preproglucagon (PPG) neurons innervate neurochemically identified autonomic neurons in the mouse brainstem

6 July 2018

1 reference

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Obesity and appetite control

6 July 2018

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Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion.

6 July 2018

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A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo

6 July 2018

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Nutrient detection by incretin hormone secreting cells

6 July 2018

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Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications

6 July 2018

1 reference

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RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis

6 July 2018

1 reference

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AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells.

6 July 2018

1 reference

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Peutz-Jeghers syndrome: a systematic review and recommendations for management

6 July 2018

1 reference

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

6 July 2018

1 reference

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Impaired gastric gland differentiation in Peutz-Jeghers syndrome

6 July 2018

1 reference

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LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo

6 July 2018

1 reference

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Mechanisms facilitating weight loss and resolution of type 2 diabetes following bariatric surgery.

6 July 2018

1 reference

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Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

LKB1 regulates pancreatic beta cell size, polarity, and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Glucose sensing in L cells: a primary cell study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons

6 July 2018

1 reference

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Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

TSC2 mediates cellular energy response to control cell growth and survival

6 July 2018

1 reference

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Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

6 July 2018

1 reference

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Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis

6 July 2018

1 reference

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Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

6 July 2018

1 reference

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Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis

6 July 2018

1 reference

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Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice

6 July 2018

1 reference

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Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

6 July 2018

1 reference

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Very high risk of cancer in familial Peutz-Jeghers syndrome

6 July 2018

1 reference

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Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Increased risk for cancer in patients with the Peutz-Jeghers syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Measurement of gut hormonal peptides in biopsies from human stomach and proximal small intestine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Is raised plasma peptide YY after intestinal resection in the rat responsible for the trophic response?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Peutz-Jeghers syndrome: quantitative study on enterochromaffin cells in hamartomatous intestine polyps.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Gut hypertrophy after gastric bypass is associated with increased glucagon-like peptide 2 and intestinal crypt cell proliferation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Over-expression of AMP-activated protein kinase impairs pancreatic {beta}-cell function in vivo

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213731

Identification of genes required for cytoplasmic localization in early C. elegans embryos

27 October 2018

1 reference

12 December 2020

Mechanical characteristics of the cat pylorus

1 reference

12 December 2020

Body condition scoring: a rapid and accurate method for assessing health status in mice

1 reference

12 December 2020

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

1 reference

12 December 2020

Identifiers

DOI

10.1242/DMM.014720

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25190708%20AND%20SRC:MED&resulttype=core&format=json