(Q34427630)

2 August 2017

title

Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells (English)

1 reference

2 August 2017

Xiang Shen

1

1 reference

2 August 2017

Hongyu Ying

series ordinal

2

1 reference

2 August 2017

Beatrice Y J T Yue

series ordinal

3

1 reference

2 August 2017

language of work or name

English

0 references

publication date

13 September 2012

1 reference

2 August 2017

1 reference

2 August 2017

volume

7

1 reference

2 August 2017

issue

9

1 reference

2 August 2017

page(s)

e44902

1 reference

Creative Commons CC0 License

2 August 2017

copyright license

start time

13 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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Perfusion-cultured bovine anterior segments as an ex vivo model for studying glucocorticoid-induced ocular hypertension and glaucoma

6 July 2018

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Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.

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Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations

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Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers

6 July 2018

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6 July 2018

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Pro370Leu mutant myocilin impairs mitochondrial functions in human trabecular meshwork cells.

6 July 2018

1 reference

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Myocilin is a modulator of Wnt signaling

6 July 2018

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Extracellular matrix turnover and outflow resistance

6 July 2018

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Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork

6 July 2018

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The role of the actomyosin system in regulating trabecular fluid outflow

6 July 2018

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Characterization of monoclonal antibodies against the glaucoma-associated protein myocilin

6 July 2018

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Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

6 July 2018

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Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure

6 July 2018

1 reference

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Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells

6 July 2018

1 reference

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Wnt signaling and human diseases: what are the therapeutic implications?

6 July 2018

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WNT/Frizzled signaling in eye development and disease

6 July 2018

1 reference

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Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

6 July 2018

1 reference

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Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

6 July 2018

1 reference

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6 July 2018

1 reference

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Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Genetic dissection of myocilin glaucoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Myocilin and glaucoma: facts and ideas.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Altered secretion of a TIGR/MYOC mutant lacking the olfactomedin domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Regulation of trabecular meshwork contractility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Identification of a gene that causes primary open angle glaucoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

The extracellular matrix and its modulation in the trabecular meshwork

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Transduction of TAT fusion proteins into the human and bovine trabecular meshwork

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Overexpression of myocilin in cultured human trabecular meshwork cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Distribution of myocilin, a glaucoma gene product, in human corneal fibroblasts

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Loss of cell-matrix cohesiveness after phagocytosis by trabecular meshwork cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Primary open-angle glaucoma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441605

Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Editorial: The drainage of aqueous humor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0044902

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference