(Q34428659)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

2

1 reference

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9 March 2020

author name string

Tom L Van Belle

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Tom Boonefaes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Xiao-Qing Wei

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Georges Leclercq

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Johan Grooten

6

1 reference

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9 March 2020

language of work or name

English

0 references

publication date

20 September 2012

1 reference

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9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

7

1 reference

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9 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

e45299

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

20 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells

6 July 2018

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IL-15 regulates both quantitative and qualitative features of the memory CD8 T cell pool

6 July 2018

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Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

6 July 2018

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Safety and immunologic effects of IL-15 administration in nonhuman primates

6 July 2018

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In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

6 July 2018

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Homeostasis of naive and memory T cells

6 July 2018

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IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response

6 July 2018

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Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

6 July 2018

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IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine

6 July 2018

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Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells

6 July 2018

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CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

6 July 2018

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Antiviral CD4+ memory T cells are IL-15 dependent

6 July 2018

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IL-15/IL-15 receptor biology: a guided tour through an expanding universe

6 July 2018

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Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis

6 July 2018

1 reference

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Naive and memory CD4+ T cell survival controlled by clonal abundance

6 July 2018

1 reference

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

6 July 2018

1 reference

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Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 is elevated in serum patients with type 1 diabetes mellitus

6 July 2018

1 reference

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IL-15 and IL-15Ralpha in CD4+T cell immunity

6 July 2018

1 reference

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IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory

6 July 2018

1 reference

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Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance

6 July 2018

1 reference

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

6 July 2018

1 reference

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IL-7 promotes the transition of CD4 effectors to persistent memory cells

6 July 2018

1 reference

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Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity

6 July 2018

1 reference

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Cytokine control of memory T-cell development and survival

6 July 2018

1 reference

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Inhibition of human CD4(+)CD25(+high) regulatory T cell function

6 July 2018

1 reference

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

6 July 2018

1 reference

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Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

6 July 2018

1 reference

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Studies of T-cell activation in chronic inflammation

6 July 2018

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6 July 2018

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Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

6 July 2018

1 reference

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T cell-independent interleukin 15Ralpha signals are required for bystander proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Interleukin 15: biology and relevance to human disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

The role of interleukin 15 in mounting an immune response against microbial infections.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

T-cell turnover in vivo and the role of cytokines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-kappaB site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Detection of IL-12, IL-13, and IL-15 messenger ribonucleic acid in the thyroid of patients with autoimmune thyroid disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-2 knockout recipient mice reject islet cell allografts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8alphaalpha IELs.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Interleukin-15 stimulates macrophages to activate CD4+ T cells: a role in the pathogenesis of rheumatoid arthritis?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 induces type 1 and type 2 CD4+ and CD8+ T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12 / IL-4 stimulation in vitro.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

CD4+CD25high regulatory cells in human peripheral blood

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15, an immunomodulator of T cell responses in intracellular infection

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Activation of naive and memory T cells by interleukin-15.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

27 October 2018

1 reference

12 December 2020

High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro

1 reference

12 December 2020

IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells

1 reference

12 December 2020

Serum interleukin-15 is elevated in systemic lupus erythematosus

1 reference

12 December 2020

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

1 reference

12 December 2020

Interleukin 15: a proinflammatory role in rheumatoid arthritis synovitis

1 reference

12 December 2020

Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens

1 reference

12 December 2020

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0045299

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23028916

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json