(Q34428724)

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The ESAT-6 protein of Mycobacterium tuberculosis interacts with beta-2-microglobulin (β2M) affecting antigen presentation function of macrophage

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Europe PubMed Central

2 August 2017

The ESAT-6 protein of Mycobacterium tuberculosis interacts with beta-2-microglobulin (β2M) affecting antigen presentation function of macrophage (English)

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Europe PubMed Central

2 August 2017

Mycobacterium tuberculosis

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7 June 2020

Sangita Mukhopadhyay

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7 June 2020

author name string

Gopalkrishna Sreejit

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7 June 2020

Asma Ahmed

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7 June 2020

Vishwanath Jha

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7 June 2020

Vijaya Lakshmi Valluri

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7 June 2020

Sudip Ghosh

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7 June 2020

publication date

30 October 2014

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2 August 2017

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7 June 2020

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7 June 2020

10

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7 June 2020

e1004446

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7 June 2020

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Creative Commons Attribution 4.0 International

30 October 2014

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ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

1 reference

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Potential role for ESAT6 in dissemination of M. tuberculosis via human lung epithelial cells.

1 reference

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Evasion and subversion of antigen presentation by Mycobacterium tuberculosis

1 reference

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Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole

1 reference

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6 July 2018

Mycobacterium tuberculosis secretory proteins CFP-10, ESAT-6 and the CFP10:ESAT6 complex inhibit lipopolysaccharide-induced NF-kappaB transactivation by downregulation of reactive oxidative species (ROS) production

1 reference

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6 July 2018

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages

1 reference

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Diagnosis and treatment of tuberculous pleural effusion in 2006.

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Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kappaB-dependent pathway

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6 July 2018

The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression

1 reference

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Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles.

1 reference

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6 July 2018

The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Interplay between mycobacteria and host signalling pathways

1 reference

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6 July 2018

The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

1 reference

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Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis

1 reference

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6 July 2018

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214792

6 July 2018

Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

1 reference

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6 July 2018

The epitope recognized by pan-HLA class I-reactive monoclonal antibody W6/32 and its relationship to unusual stability of the HLA-B27/beta2-microglobulin complex

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The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria

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Mechanisms of MHC class I--restricted antigen processing

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Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection

1 reference

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1 reference

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Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity.

1 reference

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1 reference

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1 reference

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1 reference

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27 October 2018

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1 reference

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12 December 2020

based on heuristic

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CD4+ and CD8+ T cells mediate adoptive immunity to aerosol infection of Mycobacterium bovis bacillus Calmette-Guérin

1 reference

https://pubmed.ncbi.nlm.nih.gov/25356553

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based on heuristic

inferred from PubMed ID database lookup

Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Beta 2 microglobulin in pleural effusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25356553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of human and bovine β2-microglobulins with detergent solubilized HLA-A,B antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/25356553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tuberculous pleural effusions: lymphocyte phenotypes in comparison with other lymphocyte-rich effusions

1 reference

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inferred from PubMed ID database lookup

M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25356553

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1004446

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356553%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356553%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356553%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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