(Q34430940)

2 August 2017

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title

IKK alpha on center stage (English)

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2 August 2017

J A DiDonato

1

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2 August 2017

publication date

28 August 2001

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Science's STKE : signal transduction knowledge environment

2 August 2017

published in

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2 August 2017

volume

2001

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2 August 2017

issue

97

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2 August 2017

page(s)

pe1

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

2 August 2017

cites work

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https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Role of Rel/NF-kappaB transcription factors during the outgrowth of the vertebrate limb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

NF-kappaB determines localization and features of cell death in epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

IKKalpha controls formation of the epidermis independently of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Abnormal expression and processing of keratins in pupoid fetus (pf/pf) and repeated epilation (Er/Er) mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Nuclear factor kappa B-inducing kinase and Ikappa B kinase-alpha signal skeletal muscle cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

IkappaB kinase alpha is essential for mature B cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.97.PE1

21 January 2018

Identifiers

DOI

10.1126/STKE.2001.97.PE1

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2 August 2017

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