(Q34431387)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23029547%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells (English)

1 reference

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9 March 2020

0 references

1 reference

3

1 reference

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9 March 2020

Ole William Petersen

4

1 reference

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9 March 2020

Annika Jögi

9

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9 March 2020

author name string

Marica Vaapil

1

1 reference

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9 March 2020

Karolina Helczynska

2

1 reference

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9 March 2020

Elisabet Johansson

5

1 reference

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9 March 2020

Siv Beckman

6

1 reference

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9 March 2020

Christer Larsson

7

1 reference

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9 March 2020

Sven Påhlman

8

1 reference

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9 March 2020

language of work or name

English

0 references

publication date

28 September 2012

1 reference

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full work available at URL

9 March 2020

number of pages

12

0 references

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0046543&type=printable

0 references

published in

PLOS One

1 reference

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9 March 2020

volume

7

1 reference

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9 March 2020

issue

9

1 reference

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9 March 2020

page(s)

e46543

1 reference

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Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

28 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1

6 July 2018

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Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion

6 July 2018

1 reference

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The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

6 July 2018

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Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer

6 July 2018

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Three-dimensional context regulation of metastasis

6 July 2018

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E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas.

6 July 2018

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Detection and characterization of tumor hypoxia using pO2 histography

6 July 2018

1 reference

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Cell shape regulates global histone acetylation in human mammary epithelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Hypoxia-inducible factors, stem cells, and cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Evidence for a stem cell hierarchy in the adult human breast

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Hypoxic regulation of Id-1 and activation of the unfolded protein response are aberrant in neuroblastoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

6 July 2018

1 reference

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Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain

6 July 2018

1 reference

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The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Genomic imprinting and environment in hereditary paraganglioma

6 July 2018

1 reference

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Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Tissue architecture: the ultimate regulator of breast epithelial function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Helix-loop-helix proteins in mammary gland development and breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Id-1 as a molecular target in therapy for breast cancer cell invasion and metastasis

6 July 2018

1 reference

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Targeting HIF-1 for cancer therapy

6 July 2018

1 reference

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Overexpression of Id-1 is associated with poor clinical outcome in node negative breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Signaling pathways in mammary gland development.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Id-1, ITF-2, and Id-2 comprise a network of helix-loop-helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Molecular cloning and characterization of a zinc finger protein involved in Id-1-stimulated mammary epithelial cell growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Unique expression pattern of the alpha6beta4 integrin and laminin-5 in human prostate carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Laminin mediates tissue-specific gene expression in mammary epithelia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Peripheral neuroblastic tumors and congenital heart disease. Possible role of hypoxic states in tumor induction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in ?pure? ductal carcinoma in situ of the breast

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Radial Scars in Benign Breast-Biopsy Specimens and the Risk of Breast Cancer

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460905

Prognostic implication of laminin-5 gamma 2 chain expression in the invasive front of colorectal cancers, disclosed by area-specific four-point tissue microarrays

9 December 2018

1 reference

12 December 2020

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma

1 reference

12 December 2020

Risk of neoplastic transformation in asymptomatic radial scar. Analysis of 117 cases

1 reference

12 December 2020

Induction ofID2Expression by Hypoxia-inducible Factor-1

1 reference

12 December 2020

Complexity of expression of antigenic determinants, recognized by monoclonal antibodies HMFG-1 and HMFG-2, in normal and malignant human mammary epithelial cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0046543

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23029547%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23029547%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23029547

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23029547%20AND%20SRC:MED&resulttype=core&format=json