(Q34438059)

2 August 2017

title

Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback (English)

1 reference

2 August 2017

Lingling Duan

1

1 reference

2 August 2017

Melanie H Cobb

series ordinal

2

1 reference

2 August 2017

language of work or name

English

0 references

publication date

6 December 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

1 reference

2 August 2017

volume

107

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2 August 2017

issue

51

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2 August 2017

page(s)

22314-22319

1 reference

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

2 August 2017

cites work

1 reference

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Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling

6 July 2018

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C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

6 July 2018

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A dimerization-dependent mechanism drives RAF catalytic activation

6 July 2018

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KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals

6 July 2018

1 reference

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BRAF signaling and targeted therapies in melanoma

6 July 2018

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Glucose, regulator of survival and phenotype of pancreatic beta cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Calcineurin/NFAT signaling in the beta-cell: From diabetes to new therapeutics

6 July 2018

1 reference

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B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding

6 July 2018

1 reference

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Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway

6 July 2018

1 reference

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Intrinsic regulators of pancreatic beta-cell proliferation

6 July 2018

1 reference

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Inhibition of glucose-stimulated activation of extracellular signal-regulated protein kinases 1 and 2 by epinephrine in pancreatic beta-cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Regulation and role of Raf-1/B-Raf heterodimerization

6 July 2018

1 reference

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Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization

6 July 2018

1 reference

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Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

The Rap-B-Raf signalling pathway is activated by glucose and glucagon-like peptide-1 in human islet cells

6 July 2018

1 reference

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ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Raf-1 serine 338 phosphorylation plays a key role in adhesion-dependent activation of extracellular signal-regulated kinase by epidermal growth factor.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms

6 July 2018

1 reference

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Regulation of Raf-1 by direct feedback phosphorylation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Inhibitors of the calcineurin/NFAT pathway.

6 July 2018

1 reference

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Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

6 July 2018

1 reference

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Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic beta-cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Regulation of Raf-1 activation and signalling by dephosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Regulation of insulin gene transcription by a Ca(2+)-responsive pathway involving calcineurin and nuclear factor of activated T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Active Ras induces heterodimerization of cRaf and BRaf

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Oligomerization activates c-Raf-1 through a Ras-dependent mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Transcriptional inhibition of insulin by FK506 and possible involvement of FK506 binding protein-12 in pancreatic beta-cell.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009760

Cyclosporin-induced inhibition of insulin secretion in isolated rat islets and HIT cells

27 October 2018

1 reference

12 December 2020

Inhibition of glucose-stimulated insulin release from beta TC3 cells and rodent islets by an analog of FK506

1 reference

12 December 2020

cAMP-dependent protein kinase (PKA) inhibits T cell activation by phosphorylating ser-43 of raf-1 in the MAPK/ERK pathway

1 reference

12 December 2020

Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1016630108

1 reference

2 August 2017

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2 August 2017

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