(Q34438832)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity (English)

1 reference

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15 January 2020

7

1 reference

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15 January 2020

Richard T Premont

8

1 reference

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15 January 2020

author name string

Shaowu Cheng

1

1 reference

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15 January 2020

Longxuan Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Shuangteng He

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Jun Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Yuning Sun

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Minchao He

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

William Z Suo

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

language of work or name

English

0 references

publication date

1 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

15 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

53

1 reference

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15 January 2020

page(s)

41541-41548

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

GSK3 signalling in neural development

15 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

The secretases: enzymes with therapeutic potential in Alzheimer disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

G protein-coupled receptors, cholinergic dysfunction, and Abeta toxicity in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

GRK5 deficiency leads to reduced hippocampal acetylcholine level via impaired presynaptic M2/M4 autoreceptor desensitization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

A closer look at alpha-secretase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

M1 muscarinic agonists target major hallmarks of Alzheimer's disease--the pivotal role of brain M1 receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Alois Alzheimer and Alzheimer's disease: a centennial perspective.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

GRK5 deficiency leads to early Alzheimer-like pathology and working memory impairment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Axonal transport defects: a common theme in neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

M<sub>1</sub> Muscarinic Agonists Can Modulate Some of the Hallmarks in Alzheimer's Disease: Implications in Future Therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Cell-type specific integration of cross-talk between extracellular signal-regulated kinase and cAMP signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Cellular survival: a play in three Akts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Physiology and pathology of tau protein kinases in relation to Alzheimer's disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

The critical role of cholinergic basal forebrain neurons in morphological change and memory encoding: a hypothesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

The cholinergic hypothesis of geriatric memory dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

The cholinergic hypothesis: a historical overview, current perspective, and future directions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Muscarinic acetylcholine receptor inhibition in transgenic Alzheimer-like Tg2576 mice by scopolamine favours the amyloidogenic route of processing of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimer's disease: an association with early beta-amyloid accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Dysfunction of G Protein-Coupled Receptor Kinases in Alzheimer 's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Enhanced hippocampal acetylcholine release in nociceptin-receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Pharmacological drug treatment of Alzheimer disease: the cholinergic hypothesis revisited.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

Cholinergic markers in elderly patients with early signs of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

The C-terminal tail of the M3-muscarinic receptor possesses anti-apoptotic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170894

In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009881

Cholinergic markers in Alzheimer disease

27 October 2018

1 reference

12 December 2020

Regulated secretion of beta-amyloid precursor protein in rat brain

1 reference

12 December 2020

Activation of m1 muscarinic acetylcholine receptor regulates tau phosphorylation in transfected PC12 cells

1 reference

12 December 2020

Cholinergic activity and amyloid precursor protein metabolism

1 reference

12 December 2020

G protein-coupled receptor kinases

1 reference

12 December 2020

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

12 December 2020

Modulation of ACh release from airway cholinergic nerves in horses with recurrent airway obstruction

1 reference

12 December 2020

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.170894

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041302%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

21041302

1 reference