(Q34446026)

2 August 2017

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title

Viral-based gene transfer to the mammalian CNS for functional genomic studies (English)

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2 August 2017

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Janson CG

1

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2 August 2017

McPhee SW

2

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2 August 2017

Leone P

3

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2 August 2017

Freese A

4

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2 August 2017

During MJ

5

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2 August 2017

language of work or name

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1 December 2001

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2 August 2017

Trends in Neurosciences

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2 August 2017

24

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2 August 2017

12

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2 August 2017

706-712

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Molecular analysis of neuronal physiology by gene transfer into neurons with herpes simplex virus vectors

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Modulation of rat rotational behavior by direct gene transfer of constitutively active protein kinase C into nigrostriatal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

3,400 new expressed sequence tags identify diversity of transcripts in human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

A new-generation stable inducible packaging cell line for lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Novel tools for production and purification of recombinant adenoassociated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Use of the herpes amplicon system as a vehicle for somatic gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Adenovirus-mediated transgene expression in nonhuman primate brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Cytokine production in motor neurons by poliovirus replicon vector gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Stable gene transfer to the nervous system using a non-primate lentiviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Negative-strand RNA viruses: genetic engineering and applications

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Highly stable expression of a foreign gene from rabies virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Expanding the AAV package

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Gene transfer and expression in oligodendrocytes under the control of myelin basic protein transcriptional control region mediated by adeno-associated virus

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Intracellular antibodies as a new class of therapeutic molecules for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Preclinical study on gene therapy of cervical carcinoma using adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

The spread and uptake pattern of intracerebrally administered oligonucleotides in nerve and glial cell populations of the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Controlling gene expression in living cells through small molecule-RNA interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Recombinant AAV-2 harboring gfp-antisense/ribozyme fusion sequences monitor transduction, gene expression, and show anti-HIV-1 efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Adenovirus-mediated expression of a ribozyme to c-myb mRNA inhibits smooth muscle cell proliferation and neointima formation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Adenovirus dodecahedron, a new vector for human gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Distribution of AAV-TK following intracranial convection-enhanced delivery into rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Functional genomics and rat models

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Towards an ovine model of cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Presenilins, processing of beta-amyloid precursor protein, and notch signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Metabolic regulation of brain Abeta by neprilysin.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Alpha-secretase activity of the disintegrin metalloprotease ADAM 10. Influences of domain structure

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

LRP in Alzheimer's disease: friend or foe?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Radial glial identity is promoted by Notch1 signaling in the murine forebrain

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Transgenic models of tauopathies and synucleinopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Aged Non-Human Primates: An Animal Model of Age-Associated Neurodegenerative Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Abnormally phosphorylated tau protein related to the formation of neurofibrillary tangles and neuropil threads in the cerebral cortex of sheep and goat

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Neurofibrillary tangles in the cerebral cortex of sheep

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Intraneuronal aggregate formation and cell death after viral expression of expanded polyglutamine tracts in the adult rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Overexpression of GluR6 in rat hippocampus produces seizures and spontaneous nonsynaptic bursting in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

Glutamate transport and metabolism in dopaminergic neurons of substantia nigra: implications for the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901954-8

7 January 2021

10.1016/S0166-2236(00)01954-8

Identifiers

DOI

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2 August 2017

1 reference