(Q34446282)

2 August 2017

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title

Ubiquitin proteasome pathway: implications and advances in cancer therapy (English)

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ubiquitin-proteasome system

2 August 2017

main subject

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author name string

Shah SA

series ordinal

1

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2 August 2017

Potter MW

series ordinal

2

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2 August 2017

Callery MP

series ordinal

3

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2 August 2017

publication date

1 July 2001

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2 August 2017

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2 August 2017

volume

10

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2 August 2017

issue

1-2

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2 August 2017

page(s)

43-52

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Proteasome inhibitors: valuable new tools for cell biologists

2 August 2017

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

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Catalysis by a multiprotein IkappaB kinase complex

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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7 January 2021

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Structure of lactacystin, a new microbial metabolite which induces differentiation of neuroblastoma cells

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Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone

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Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

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7 January 2021

Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

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7 January 2021

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7 January 2021

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7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

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7 January 2021

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7 January 2021

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7 January 2021

Detailed analysis of cell cycle kinetics upon proteasome inhibition

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The mechanism and functions of ATP-dependent proteases in bacterial and animal cells

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7 January 2021

Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome

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7 January 2021

Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B

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7 January 2021

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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7 January 2021

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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7 January 2021

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7 January 2021

Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter

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7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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7 January 2021

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells

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7 January 2021

Apoptosis-inducing levels of UV radiation and proteasome inhibitors produce opposite effects on p21(WAF1) in human melanoma cells

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7 January 2021

Enhancement of CPP32-like activity in the TNF-treated U937 cells by the proteasome inhibitors

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7 January 2021

Activation of the cell death program by inhibition of proteasome function

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7 January 2021

Peptidyl aldehyde inhibitors of proteasome induce apoptosis rapidly in mouse lymphoma RVC cells

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7 January 2021

Proteasomes play an essential role in thymocyte apoptosis

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7 January 2021

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

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7 January 2021

Apoptosis induced by anticancer drugs

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7 January 2021

Apoptosis. Its significance in cancer and cancer therapy

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7 January 2021

Apoptosis in cancer therapy: crossing the threshold

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7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

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7 January 2021

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

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7 January 2021

Prevention of cisplatin-DNA adduct repair and potentiation of cisplatin-induced apoptosis in ovarian carcinoma cells by proteasome inhibitors

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7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

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7 January 2021

Cell and environment interactions in tumor microregions: the multicell spheroid model

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7 January 2021

10.1016/S0960-7404(01)00018-4

Identifiers

DOI

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2 August 2017

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