(Q34453159)

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Molecular perspectives on selective estrogen receptor modulators (SERMs): progress in understanding their tissue-specific agonist and antagonist actions

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Europe PubMed Central

Molecular perspectives on selective estrogen receptor modulators (SERMs): progress in understanding their tissue-specific agonist and antagonist actions (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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David M Lonard

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

Carolyn L Smith

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

1 January 2002

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Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

67

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Europe PubMed Central

PubMed publication ID

2 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

15-24

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Estrogen receptor transcription and transactivation: Estrogen receptor knockout mice: what their phenotypes reveal about mechanisms of estrogen action

1 reference

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Coronary Artery Disease in Postmenopausal Women

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

1 reference

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7 January 2021

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Defining a minimal estrogen receptor DNA binding domain

1 reference

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7 January 2021

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Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens

1 reference

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7 January 2021

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Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

1 reference

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7 January 2021

based on heuristic

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The SRC family of nuclear receptor coactivators

1 reference

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7 January 2021

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Nuclear receptor coregulators: cellular and molecular biology

1 reference

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1 reference

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7 January 2021

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A transcriptional co-repressor that interacts with nuclear hormone receptors

1 reference

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7 January 2021

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Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

1 reference

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7 January 2021

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Cloning of a novel receptor expressed in rat prostate and ovary

1 reference

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7 January 2021

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Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene

1 reference

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7 January 2021

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The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

1 reference

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7 January 2021

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AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

1 reference

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7 January 2021

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The nuclear receptor ligand-binding domain: structure and function

1 reference

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7 January 2021

based on heuristic

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AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors

1 reference

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7 January 2021

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

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7 January 2021

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inferred from DOI database lookup

Molecular determinants of the estrogen receptor-coactivator interface

1 reference

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7 January 2021

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Molecular basis of agonism and antagonism in the oestrogen receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide antagonists of the human estrogen receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of an estrogen response element activated by metabolites of 17beta-estradiol and raloxifene

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen receptor pathways to AP-1.

1 reference

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7 January 2021

based on heuristic

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Membrane binding sites and non-genomic effects of estrogen in cultured human pre-osteoclastic cells

1 reference

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7 January 2021

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Mechanisms of estrogen action in the cardiovascular system

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of neural and signal transduction pathways for lordosis in the search for estrogen actions on the central nervous system

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Epidermal growth factor partially reverses the inhibitory effects of antiestrogens on T 47D human breast cancer cell growth

1 reference

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Changes in epidermal growth factor receptor expression and response to ligand associated with acquired tamoxifen resistance or oestrogen independence in the ZR-75-1 human breast cancer cell line

1 reference

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inferred from DOI database lookup

Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Coactivator and corepressor complexes in nuclear receptor function

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen.

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Combinatorial roles of the nuclear receptor corepressor in transcription and development

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen receptor activation function 1 works by binding p160 coactivator proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen-binding substances of target tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

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Comparative analyses of mechanistic differences among antiestrogens

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteasome-dependent degradation of the human estrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Implication of proteasome in estrogen receptor degradation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

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Degradation of nuclear oncoproteins by the ubiquitin system in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

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Structure and functions of the 20S and 26S proteasomes

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The proteasome: paradigm of a self-compartmentalizing protease

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Different classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural insights into the mode of action of a pure antiestrogen

1 reference

https://api.crossref.org/works/10.1016%2FS0039-128X%2801%2900133-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0039-128X(01)00133-7

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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