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Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
title
Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
author
Peter Igarashi
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Hui Y Lan
series ordinal
9
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Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
author name string
Xiao Ming Meng
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1
1 reference
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Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Xiao Ru Huang
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Arthur C K Chung
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Wei Qin
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Xinli Shao
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Wenjun Ju
series ordinal
7
1 reference
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PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Erwin P Bottinger
series ordinal
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
publication date
1 July 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
published in
Journal of the American Society of Nephrology
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
volume
21
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
issue
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
page(s)
1477-1487
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
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Latent TGF-beta1 protects against crescentic glomerulonephritis
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Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
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The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells.
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Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.
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Smad3 as a mediator of the fibrotic response
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Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
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Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner
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6 July 2018
Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.
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6 July 2018
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
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6 July 2018
Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis
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6 July 2018
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
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SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.
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6 July 2018
Smad2 role in mesoderm formation, left-right patterning and craniofacial development
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6 July 2018
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
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6 July 2018
Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice.
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Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice.
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27 October 2018
Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.
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27 October 2018
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013519
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27 October 2018
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27 October 2018
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013519
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27 October 2018
Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3.
1 reference
stated in
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013519
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27 October 2018
Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013519
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27 October 2018
CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013519
retrieved
27 October 2018
Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20595680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
It's a Smad world: regulation of TGF-beta signaling in the kidney
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20595680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1681/ASN.2009121244
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PMC publication ID
3013519
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PubMed publication ID
20595680
1 reference
stated in
Europe PubMed Central
PMC publication ID
3013519
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
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