(Q34463402)

2 August 2017

1 reference

title

The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs (English)

1 reference

2 August 2017

0 references

1 reference

Binder EB

1

1 reference

2 August 2017

Kinkead B

series ordinal

2

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2 August 2017

Owens MJ

series ordinal

3

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2 August 2017

Nemeroff CB

series ordinal

4

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2 August 2017

language of work or name

English

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publication date

1 December 2001

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2 August 2017

published in

Biological Psychiatry

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2 August 2017

volume

50

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2 August 2017

issue

11

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2 August 2017

page(s)

856-872

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Neurotensin binding to dopamine

2 August 2017

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Post mortem levels of thyrotropin-releasing hormone and neurotensin in the amygdala in Alzheimer's disease, schizophrenia and depression

7 January 2021

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Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.

7 January 2021

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Haloperidol but not clozapine increases neurotensin receptor mRNA levels in rat substantia nigra

7 January 2021

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CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates

7 January 2021

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Morphologically distinct subpopulations of neurotensin-immunoreactive striatal neurons observed in rat following dopamine depletions and D2 receptor blockade project to the globus pallidus.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens

7 January 2021

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Blunting of the neurotensin mRNA response to haloperidol in the striatum of aging rats: possible relationship to decline in dopamine D2 receptor expression

7 January 2021

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Effects of antipsychotic drugs on latent inhibition: sensitivity and specificity of an animal behavioral model of clinical drug action.

7 January 2021

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Numbers of neurotensin-immunoreactive neurons selectively increased in rat ventral striatum following acute haloperidol administration

7 January 2021

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D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

7 January 2021

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Further indication that distinct dopaminergic subsets project to the rat cerebral cortex: lack of colocalization with neurotensin in the superficial dopaminergic fields of the anterior cingulate, motor, retrosplenial and visual cortices

7 January 2021

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The effects of intra-accumbens neurotensin on sensorimotor gating

7 January 2021

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Pro-dopamine effects of neurotensin on sensorimotor gating deficits

7 January 2021

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Elementary neuronal dysfunctions in schizophrenia

7 January 2021

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Effects of acute and long-term treatment with neuroleptics on regional telencephalic neurotensin levels in the male rat

7 January 2021

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Neurotensin concentrations in rat striatum and nucleus accumbens: Further studies of their regulation

7 January 2021

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Receptor-receptor interactions and their relevance for receptor diversity. Focus on neuropeptide/dopamine interactions.

7 January 2021

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Intramembrane interactions between neurotensin receptors and dopamine D2 receptors as a major mechanism for the neuroleptic-like action of neurotensin

7 January 2021

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Relation of CSF neurotensin concentrations to symptoms and drug response of psychotic patients

7 January 2021

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Neurotensin innervation of the human cerebral cortex: lack of colocalization with catecholamines

7 January 2021

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Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia.

7 January 2021

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DA2/NT receptor balance in the mesostriatal and mesolimbocortical systems after chronic treatment with typical and atypical neuroleptic drugs

7 January 2021

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Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs

7 January 2021

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The modulation of corticoaccumbens transmission by limbic afferents and dopamine: a model for the pathophysiology of schizophrenia.

7 January 2021

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Latent inhibition in drug naive schizophrenics: relationship to duration of illness and dopamine D2 binding using SPET.

7 January 2021

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Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of the neurotensin receptor

7 January 2021

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Comparison of neurotensin responses to MDL 100,907, a selective 5HT2A antagonist, with clozapine and haloperidol

7 January 2021

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Dopaminergic control of 125I-labeled neurotensin binding site density in corticolimbic structures of the rat brain

7 January 2021

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Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems

7 January 2021

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Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei

7 January 2021

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Ontogeny of the effect of antipsychotic drug treatment on neurotensin concentrations in the rat brain

7 January 2021

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The sigma receptor ligand SR 31742A increases neurotensin in the nucleus accumbens but not in the caudate-putamen of the rat.

7 January 2021

1 reference

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[3H]Neurotensin receptor densities in human postmortem brain tissue obtained from normal and schizophrenic persons. An autoradiographic study

7 January 2021

1 reference

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Anatomy and Mechanisms of Neurotensin‐Dopamine Interactions in the Central Nervous System

7 January 2021

1 reference

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Characterization of the genomic structure, promoter region, and a tetranucleotide repeat polymorphism of the human neurotensin receptor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Characterization of dopaminergic influence on striatal-nigral neurotensin systems

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Effects of CI-943, a potential antipsychotic drug, and haloperidol on regional brain neurotensin concentrations

7 January 2021

1 reference

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Effects of anticholinergic drugs on regional brain neurotensin concentrations

7 January 2021

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Alterations in regional brain neurotensin concentrations produced by atypical antipsychotic drugs

7 January 2021

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BMY 14802, a potential antipsychotic drug, increases expression of proneurotensin mRNA in the rat striatum

7 January 2021

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Neurotensin peptides antagonistically regulate postsynaptic dopamine D2 receptors in rat nucleus accumbens: a receptor binding and microdialysis study

7 January 2021

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Antipsychotics and neuropeptides: the atypical profile of CI-943 and its relationship to neurotensin

7 January 2021

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Reduced CSF neurotensin concentration in drug-free schizophrenic patients

7 January 2021

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Latent inhibition: the effect of nonreinforced pre-exposure to the conditional stimulus.

7 January 2021

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Human brain distribution of neurotensin in normals, schizophrenics, and Huntington's choreics

7 January 2021

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Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain

7 January 2021

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The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

7 January 2021

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Disorders of attention and perception in early schizophrenia

7 January 2021

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c-fos antisense oligonucleotide specifically attenuates haloperidol-induced increases in neurotensin/neuromedin N mRNA expression in rat dorsal striatum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Expression of the proneurotensin gene in the rat brain and its regulation by antipsychotic drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum

7 January 2021

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Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics

7 January 2021

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Changes in the limbic neurotensin systems induced by dopaminergic drugs

7 January 2021

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Coexpression of neurotensin and c-fos mRNAs in rat neostriatal neurons following acute haloperidol

7 January 2021

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Haloperidol rapidly increases the number of neurotensin mRNA-expressing neurons in neostriatum of the rat brain

7 January 2021

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Neurotensin induces an inward current in rat mesencephalic dopaminergic neurons

7 January 2021

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Risperidone does not elevate neurotensin mRNA in rat nucleus accumbens and caudate-putamen

7 January 2021

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Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes

7 January 2021

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Pharmacological specificity of the increase in neurotensin concentrations after antipsychotic drug treatment

7 January 2021

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In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat.

7 January 2021

1 reference

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Neurotensin-like immunoreactivity in cerebrospinal fluid of patients with schizophrenia, depression, anorexia nervosa-bulimia, and premenstrual syndrome

7 January 2021

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Neuropeptides in Alzheimer's disease: a postmortem study

7 January 2021

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Regional Brain Concentrations of Neuropeptides in Huntington's Chorea and Schizophrenia

7 January 2021

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Investigations about a direct neurotensin-dopamine interaction by nuclear magnetic resonance study, synaptosomal uptake of dopamine, and binding of neurotensin to its receptors

7 January 2021

1 reference

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Pharmacological, molecular and functional characterization of glial neurotensin receptors

7 January 2021

1 reference

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The effects of neurotensin on GABA and acetylcholine release in the dorsal striatum of the rat: an in vivo microdialysis study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin receptor binding levels in basal ganglia are not altered in Huntington's chorea or schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioural, electrophysiological and anatomical data.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

The non-peptide neurotensin receptor antagonist SR48692 is not a potent antagonist of neurotensin(8-13) responses of rat substantia nigra neurones in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

The neurotensin analog xenopsin excites nigral dopamine neurons

7 January 2021

1 reference

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Effects of short- and long-term haloperidol administration and withdrawal on regional brain cholecystokinin and neurotensin concentrations in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Peptides, the limbic lobe and schizophrenia

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

D1 and D2 dopamine receptors differentially increase Fos-like immunoreactivity in accumbal projections to the ventral pallidum and midbrain

7 January 2021

1 reference

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C-fos mediates antipsychotic-induced neurotensin gene expression in the rodent striatum

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Chemical brain anatomy in schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Subsets of neurotensin-immunoreactive neurons in the rat striatal complex following antagonism of the dopamine D2 receptor: An immunohistochemical double-labeling study using antibodies against Fos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

CSF neurotensin concentrations and antipsychotic treatment in schizophrenia and schizoaffective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Effects of neurotensin on midbrain dopamine neurons: Are they mediated by formation of a neurotensin?dopamine complex?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin modulates autoreceptor mediated dopamine effects on midbrain dopamine cell activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Actions of neurotensin: a review of the electrophysiological studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Dopamine-mediated changes in central nervous system neurotensin systems: a role for NMDA receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Differential effects of neurotensin on dopamine release in the caudal and rostral nucleus accumbens: a combined in vivo electrochemical and electrophysiological study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Effects of neurotensin in a rodent model of tardive dyskinesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Cross-species studies of sensorimotor gating of the startle reflex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Structure and functional expression of the cloned rat neurotensin receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin and cholecystokinin octapeptide control synergistically dopamine release and dopamine D2 receptor affinity in rat neostriatum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Facilitation of GABA release by neurotensin is associated with a reduction of dopamine release in rat nucleus accumbens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin counteracts apomorphine-induced inhibition of dopamine release as studied by microdialysis in rat neostriatum.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Acute effects of D-1 and D-2 dopamine receptor agonist and antagonist drugs on basal ganglia [Met5]- and [Leu5]-enkephalin and neurotensin content in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Chronic neuroleptic treatment enhances neurotensin receptor binding in human and rat substantia nigra

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin modulates the binding characteristics of dopamine D2 receptors in rat striatal membranes also following treatment with toluene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neurotensin Decreases the Affinity of Dopamine D2Agonist Binding by a G Protein-Independent Mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Dopamine D2-receptors regulate neurotensin release from nucleus accumbens and striatum as measured by in vivo microdialysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Molecular and behavioral effects mediated by Gs-coupled adenosine A2a, but not serotonin 5-Ht4 or 5-Ht6 receptors following antipsychotic administration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Identification of a polymorphism in the human neurotensin receptor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: a search for common ground

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

The switching model of latent inhibition: an update of neural substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Subnormal CSF levels of neurotensin in a subgroup of schizophrenic patients: normalization after neuroleptic treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

The effect of acute haloperidol treatment on brain proneurotensin mRNA: in situ hybridization analyses using a novel fluorescence detection procedure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Autoradiographic characterization of neurotensin receptors in the entorhinal cortex of schizophrenic patients and control subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Subsets of neurotensin-immunoreactive neurons revealed following antagonism of the dopamine-mediated suppression of neurotensin immunoreactivity in the rat striatum.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Distinct and interactive effects of d-amphetamine and haloperidol on levels of neurotensin and its mRNA in subterritories in the dorsal and ventral striatum of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Temporal dissociation of neurotensin/neuromedin N mRNA expression in topographically separate subsets of rat striatal neurons following administration of haloperidol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Neuropeptides in the amygdala of controls, schizophrenics and patients suffering from Huntington's chorea: an immunohistochemical study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

Solubilization and purification of a high affinity neurotensin receptor from newborn human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901211-2

10.1016/S0006-3223(01)01211-2

7 January 2021

Identifiers

DOI

1 reference

2 August 2017

1 reference