(Q34466861)

2 August 2017

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title

Advancing host-directed therapy for tuberculosis. (English)

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2 August 2017

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Robert S Wallis

1

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PubMed ID

25765201

2 August 2017

Richard Hafner

series ordinal

2

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2 August 2017

13 March 2015

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Nature Reviews Immunology

2 August 2017

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2 August 2017

15

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2 August 2017

4

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2 August 2017

255-263

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Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis

2 August 2017

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A four-month gatifloxacin-containing regimen for treating tuberculosis

21 January 2018

1 reference

High-dose rifapentine with moxifloxacin for pulmonary tuberculosis

21 January 2018

1 reference

A trial of mass isoniazid preventive therapy for tuberculosis control

21 January 2018

1 reference

Pulmonary impairment after tuberculosis and its contribution to TB burden

21 January 2018

1 reference

Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis

21 January 2018

1 reference

Macrophages in tuberculosis: friend or foe.

21 January 2018

1 reference

Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens

21 January 2018

1 reference

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis

21 January 2018

1 reference

Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda

21 January 2018

1 reference

Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits

21 January 2018

1 reference

Novel STAT1 alleles in a patient with impaired resistance to mycobacteria.

21 January 2018

1 reference

A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection

21 January 2018

1 reference

Failure to control growth of mycobacteria in blood from children infected with human immunodeficiency virus and its relationship to T cell function

21 January 2018

1 reference

Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG.

21 January 2018

1 reference

Letting sleeping dos lie: does dormancy play a role in tuberculosis?

21 January 2018

1 reference

Appropriate DevR (DosR)-mediated signaling determines transcriptional response, hypoxic viability and virulence of Mycobacterium tuberculosis

21 January 2018

1 reference

Longevity loss among cured tuberculosis patients and the potential value of prevention

21 January 2018

1 reference

Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response

21 January 2018

1 reference

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

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Role of autophagy in the host response to microbial infection and potential for therapy

21 January 2018

1 reference

Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

21 January 2018

1 reference

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.

21 January 2018

1 reference

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

1 reference

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

21 January 2018

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Identification of human-selective analogues of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

21 January 2018

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Identification of a candidate therapeutic autophagy-inducing peptide

21 January 2018

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Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth

21 January 2018

1 reference

Abelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophages

21 January 2018

1 reference

Imatinib-sensitive tyrosine kinases regulate mycobacterial pathogenesis and represent therapeutic targets against tuberculosis

21 January 2018

1 reference

Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components

21 January 2018

1 reference

Large-scale imatinib dose-concentration-effect study in CML patients under routine care conditions.

21 January 2018

1 reference

The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen

21 January 2018

1 reference

Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R

21 January 2018

1 reference

Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa

21 January 2018

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Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

Vitamin D as supplementary treatment for tuberculosis: a double-blind, randomized, placebo-controlled trial.

21 January 2018

1 reference

L-arginine and vitamin D adjunctive therapies in pulmonary tuberculosis: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

21 January 2018

1 reference

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment

21 January 2018

1 reference

Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator

21 January 2018

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Phenylbutyrate induces antimicrobial peptide expression

21 January 2018

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Vitamin D₃ and phenylbutyrate promote development of a human dendritic cell subset displaying enhanced antimicrobial properties

21 January 2018

1 reference

Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis

21 January 2018

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Performance of the MTBDRsl assay in Georgia

21 January 2018

1 reference

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

Metformin, an antidiabetic agent, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro

21 January 2018

1 reference

Metformin as adjunct antituberculosis therapy

21 January 2018

1 reference

Immunomodulation with recombinant interferon-gamma1b in pulmonary tuberculosis

21 January 2018

1 reference

Randomized trial of adjunctive interleukin-2 in adults with pulmonary tuberculosis.

21 January 2018

1 reference

Antibody-mediated immunity against tuberculosis: implications for vaccine development

21 January 2018

1 reference

Therapeutic efficacy of high-dose intravenous immunoglobulin in Mycobacterium tuberculosis infection in mice

21 January 2018

1 reference

Adjunctive corticosteroid therapy for tuberculosis: a critical reappraisal of the literature

21 January 2018

1 reference

Corticosteroids for prevention of mortality in people with tuberculosis: a systematic review and meta-analysis

21 January 2018

1 reference

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections

21 January 2018

1 reference

Month 2 culture status and treatment duration as predictors of tuberculosis relapse risk in a meta-regression model

21 January 2018

1 reference

Immunoadjuvant prednisolone therapy for HIV-associated tuberculosis: a phase 2 clinical trial in Uganda.

21 January 2018

1 reference

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

21 January 2018

1 reference

The potential for disease modification in Crohn's disease

21 January 2018

1 reference

Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-cont

21 January 2018

1 reference

A study of the safety, immunology, virology, and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis

21 January 2018

1 reference

Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

Etanercept for the treatment of stage II and III progressive pulmonary sarcoidosis

21 January 2018

1 reference

Mathematical modeling of the cause of tuberculosis during tumor necrosis factor blockade

21 January 2018

1 reference

Glucocorticoid use, other associated factors, and the risk of tuberculosis

21 January 2018

1 reference

Effectiveness of recommendations to prevent reactivation of latent tuberculosis infection in patients treated with tumor necrosis factor antagonists

21 January 2018

1 reference

Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three-year prospective French Research Axed on Tolerance of Biotherapies registry

21 January 2018

1 reference

Therapeutic use of infliximab in tuberculosis to control severe paradoxical reaction of the brain and lymph nodes.

21 January 2018

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Adalimumab treatment of life-threatening tuberculosis.

21 January 2018

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Risk of tuberculosis reactivation with tofacitinib (CP-690550).

21 January 2018

1 reference

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

21 January 2018

1 reference

Tuberculous meningitis-related optic neuritis: recovery of vision with thalidomide in 4 consecutive cases

21 January 2018

1 reference

Intractable intracranial tuberculous infection responsive to thalidomide: report of four cases

21 January 2018

1 reference

Adjunctive thalidomide therapy for childhood tuberculous meningitis: results of a randomized study

21 January 2018

1 reference

Identification of a primary target of thalidomide teratogenicity

21 January 2018

1 reference

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

21 January 2018

1 reference

Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro

21 January 2018

1 reference

Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice

21 January 2018

1 reference

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs

21 January 2018

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Adjuvant host-directed therapy with types 3 and 5 but not type 4 phosphodiesterase inhibitors shortens the duration of tuberculosis treatment

21 January 2018

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Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model

21 January 2018

1 reference

Pentoxifylline treatment of mice with chronic pulmonary tuberculosis accelerates the development of destructive pathology

21 January 2018

1 reference

Pentoxifylline therapy in human immunodeficiency virus-seropositive persons with tuberculosis: a randomized, controlled trial

21 January 2018

1 reference

Pentoxifylline in human immunodeficiency virus- positive tuberculosis: safety at 4 years

21 January 2018

1 reference

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

21 January 2018

1 reference

Increased release of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha by bronchoalveolar cells lavaged from involved sites in pulmonary tuberculosis

21 January 2018

1 reference

Aspirin and ibuprofen enhance pyrazinamide treatment of murine tuberculosis

21 January 2018

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Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis.

21 January 2018

1 reference

Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.

21 January 2018

1 reference

Simvastatin increases the in vivo activity of the first-line tuberculosis regimen

21 January 2018

1 reference

The effects of statin use on the development of tuberculosis among patients with diabetes mellitus

21 January 2018

1 reference

Mycobacterium tuberculosis activates human macrophage peroxisome proliferator-activated receptor gamma linking mannose receptor recognition to regulation of immune responses

21 January 2018

1 reference

Clinical studies on the management of periodontal diseases utilizing subantimicrobial dose doxycycline (SDD).

21 January 2018

1 reference

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases

21 January 2018

1 reference

Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial.

21 January 2018

1 reference

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis.

21 January 2018

1 reference

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis.

21 January 2018

1 reference

Chronic obstructive airways disease following treated pulmonary tuberculosis

21 January 2018

1 reference

Relationship of the manifestations of tuberculosis to CD4 cell counts in patients with human immunodeficiency virus infection

21 January 2018

1 reference

HIV-1 and recurrence, relapse, and reinfection of tuberculosis after cure: a cohort study in South African mineworkers

21 January 2018

1 reference

Recurrent TB: relapse or reinfection? The effect of HIV in a general population cohort in Malawi

21 January 2018

1 reference

Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study

21 January 2018

1 reference

Accelerated course of human immunodeficiency virus infection after tuberculosis

21 January 2018

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Timing of initiation of antiretroviral drugs during tuberculosis therapy

21 January 2018

1 reference

A delicate dance: host response to mycobacteria

21 January 2018

1 reference

Whole Blood Bactericidal Activity during Treatment of Pulmonary Tuberculosis

21 January 2018

1 reference

A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effects on clinical response and nutritional status

21 January 2018

1 reference

Corticosteroid effects on sputum culture in pulmonary tuberculosis: a meta-regression analysis

31 March 2020

1 reference

Study of chemotherapy regimens of 5 and 7 months' duration and the role of corticosteroids in the treatment of sputum-positive patients with pulmonary tuberculosis in South India

31 March 2020

1 reference

Granulomatous infections due to tumor necrosis factor blockade: correction

31 March 2020

1 reference

The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial

31 March 2020

1 reference

THALIDOMIDE IN THE TREATMENT OF LEPRA REACTIONS

31 March 2020

1 reference

Increased interleukin-1 production and monocyte suppressor cell activity associated with human tuberculosis

31 March 2020

1 reference

Assessment of serum IL-1, IL-2 and IFN-γ levels in untreated pulmonary tuberculosis patients: role in pathogenesis

31 March 2020

1 reference

Serum MMPs 7-9 and their inhibitors during glucocorticoid and anti-TNF-α therapy in pediatric inflammatory bowel disease

31 March 2020

1 reference

Pharmacological modulation of TNF production in macrophages

31 March 2020

1 reference

12 December 2020

Assessment of long term status of sputum positive pulmonary TB patients successfully treated with short course chemotherapy.

1 reference

12 December 2020

Recent development in pleiotropic effects of statins on cardiovascular disease through regulation of transforming growth factor-beta superfamily

1 reference

12 December 2020

The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion

1 reference

12 December 2020

CORTICOSTEROIDS IN PULMONARY TUBERCULOSIS. I. OVER-ALL RESULTS IN MADISON-MINNEAPOLIS VETERANS ADMINISTRATION HOSPITALS STEROID STUDY

1 reference

12 December 2020

The after-history of pulmonary tuberculosis. VI. The first fifteen years following diagnosis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI3813

1 reference

2 August 2017

1 reference

PubMed ID

25765201