(Q34467542)

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Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling

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Europe PubMed Central

PubMed publication ID

2 August 2017

Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Xiaoyu Chen

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Bo Bai

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Yanjun Tian

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Hui Du

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Jing Chen

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

30 September 2014

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Europe PubMed Central

PubMed publication ID

2 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

2 August 2017

289

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

45

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

31173-31187

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Heterodimerization of mouse orexin type 2 receptor variants and the effects on signal transduction

1 reference

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A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine

1 reference

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6 July 2018

APJ acts as a dual receptor in cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors

1 reference

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6 July 2018

Apelin, diabetes, and obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.

1 reference

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6 July 2018

Application of G protein-coupled receptor-heteromer identification technology to monitor β-arrestin recruitment to G protein-coupled receptor heteromers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Beyond desensitization: physiological relevance of arrestin-dependent signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Modular mass spectrometric tool for analysis of composition and phosphorylation of protein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Beta-arrestins and cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Arrestins: ubiquitous regulators of cellular signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Charged residues of the conserved DRY triplet of the vasopressin V1a receptor provide molecular determinants for cell surface delivery and internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Transduction of receptor signals by beta-arrestins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Genomic organization of mouse orexin receptors: characterization of two novel tissue-specific splice variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Single-step perfusion chromatography with a throughput potential for enhanced peptide detection by matrix-assisted laser desorption/ ionization-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

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The Role of a Conserved Region of the Second Intracellular Loop in AT1 Angiotensin Receptor Activation and Signaling

1 reference

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6 July 2018

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Seven-transmembrane receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin (65-77) activates extracellular signal-regulated kinases via a PTX-sensitive G protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

1 reference

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6 July 2018

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

6 July 2018

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

1 reference

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6 July 2018

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

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6 July 2018

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223320

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Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways

1 reference

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6 July 2018

Value of novelty?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Heterodimerization of human apelin and kappa opioid receptors: roles in signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Real-time detection of interactions between the human oxytocin receptor and G protein-coupled receptor kinase-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Agonist-dependent internalization of the angiotensin II type one receptor (AT1): role of C-terminus phosphorylation in recruitment of beta-arrestins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Role of ßarrestins in bradykinin B2 receptor-mediated signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Apelin protects myocardial injury induced by isoproterenol in rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574020

21 January 2018

Association of beta-Arrestin 1 with the type 1A angiotensin II receptor involves phosphorylation of the receptor carboxyl terminus and correlates with receptor internalization

1 reference

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27 October 2018

Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology

1 reference

https://pubmed.ncbi.nlm.nih.gov/25271156

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.574020

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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