(Q34469022)

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Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis.

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17 February 2020

Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis (English)

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17 February 2020

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17 February 2020

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Nadia Hashash

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17 February 2020

Anthony L Johnson

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17 February 2020

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25 October 2012

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17 February 2020

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17 February 2020

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17 February 2020

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17 February 2020

e1002978

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17 February 2020

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Creative Commons Attribution 4.0 International

25 October 2012

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Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formation

1 reference

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1 reference

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1 reference

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The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage

1 reference

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Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress

1 reference

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Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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In vivo analysis of chromosome condensation in Saccharomyces cerevisiae

1 reference

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Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast

1 reference

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Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites

1 reference

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Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability

1 reference

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6 July 2018

The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distress

1 reference

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Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of the S. cerevisiae DNA helicase Rrm3p

1 reference

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The Spindle Assembly and Spindle Position Checkpoints

1 reference

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ATR Regulates Fragile Site Stability

1 reference

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6 July 2018

Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis

1 reference

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Replication fork collapse at replication terminator sequences

1 reference

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In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin

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The DNA replication checkpoint response stabilizes stalled replication forks

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Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

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DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae

1 reference

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The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage

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1 reference

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Mitotic chromosome condensation requires Brn1p, the yeast homologue of Barren

1 reference

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The importance of repairing stalled replication forks

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

1 reference

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1 reference

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6 July 2018

Induction of sister chromatid exchanges at common fragile sites

1 reference

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6 July 2018

A replication fork barrier at the 3' end of yeast ribosomal RNA genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486896

6 July 2018

Rodent common fragile sites: are they conserved? Evidence from mouse and rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486896

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ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

1 reference

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Interplay between ATM and ATR in the regulation of common fragile site stability

1 reference

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21 January 2018

Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites.

1 reference

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Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription.

1 reference

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1 reference

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1 reference

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Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae.

1 reference

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21 January 2018

DNA replication checkpoint prevents precocious chromosome segregation by regulating spindle behavior

1 reference

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21 January 2018

Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast

1 reference

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DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1 reference

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21 January 2018

Direct Coupling Between Meiotic DNA Replication and Recombination Initiation

2 references

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21 January 2018

https://pubmed.ncbi.nlm.nih.gov/23133392

12 December 2020

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Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange

1 reference

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Heritable Fragile Site on Chromosome 16: Probable Localization of Haptoglobin Locus in Man

1 reference

https://pubmed.ncbi.nlm.nih.gov/23133392

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Premitotic chromosome individualization in mammalian cells depends on topoisomerase II activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23133392

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Common fragile sites in man and three closely related primate species

1 reference

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Stretching DNA with a receding meniscus: Experiments and models

1 reference

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based on heuristic

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The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

1 reference

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1 reference

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based on heuristic

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Identifiers

10.1371/JOURNAL.PGEN.1002978

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133392%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133392%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133392%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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