(Q34470786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

6

1 reference

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10 March 2020

author name string

Yukihiro Chino

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Yoshishige Samukawa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Soichi Sakai

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Yasuhiro Nakai

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Jun-ichi Yamaguchi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Ikumi Tamai

7

1 reference

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10 March 2020

publication date

6 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

Biopharmaceutics and Drug Disposition

10 March 2020

published in

1 reference

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10 March 2020

volume

35

1 reference

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10 March 2020

issue

7

1 reference

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10 March 2020

page(s)

391-404

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

Safety, pharmacokinetics, and pharmacodynamics of single and multiple luseogliflozin dosing in healthy Japanese males: a randomized, single-blind, placebo-controlled trial.

10 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Renal glucose reabsorption inhibitors to treat diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Abnormal expression and dysfunction of novel SGLT2 mutations identified in familial renal glucosuria patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Uric acid transport and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

(1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Sodium glucose cotransporter 2 inhibitors as a new treatment for diabetes mellitus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Elevated serum uric acid concentrations independently predict cardiovascular mortality in type 2 diabetic patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

SLC2A9 is a high-capacity urate transporter in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Human renal organic anion transporter 4 operates as an asymmetric urate transporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

The association between serum uric acid level and long-term incidence of hypertension: Population-based cohort study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

ON THE INCREASED URIC ACID CLEARANCE FOLLOWING THE INTRAVENOUS INFUSION OF HYPERTONIC GLUCOSE SOLUTIONS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Molecular identification of a renal urate anion exchanger that regulates blood urate levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Effect of insulin on uric acid excretion in humans.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Renal hypouricaemia in insulin treated diabetes mellitus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Effects of intraluminal D-glucose and probenecid on urate absorption in the rat proximal tubule

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial

6 July 2018

1 reference

Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial

21 January 2018

1 reference

Efficacy and safety of ipragliflozin in patients with type 2 diabetes inadequately controlled on metformin: a dose-finding study.

21 January 2018

1 reference

A Phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes

21 January 2018

1 reference

Significance of hyperuricemia on the early detection of renal failure in a cohort of screened subjects

21 January 2018

1 reference

Relationship of uric acid with progression of kidney disease.

21 January 2018

1 reference

Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals

21 January 2018

1 reference

Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans

21 January 2018

1 reference

Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter.

21 January 2018

1 reference

Haemoglobin A1c, fasting glucose, serum C-peptide and insulin resistance in relation to serum uric acid levels--the Third National Health and Nutrition Examination Survey

21 January 2018

1 reference

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

21 January 2018

1 reference

Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate.

21 January 2018

1 reference

Functional cooperation of SMCTs and URAT1 for renal reabsorption transport of urate

21 January 2018

1 reference

The interaction between uric acid level and other risk factors on the development of gout among asymptomatic hyperuricemic men in a prospective study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223977

Prevalence of the metabolic syndrome in individuals with hyperuricemia

27 October 2018

1 reference

12 December 2020

Uric acid and diabetes: observations in a population study

1 reference

12 December 2020

Diabetes, prediabetes and uricaemia

1 reference

12 December 2020

Uric acid as an independent risk factor in the treatment of hypertension

1 reference

12 December 2020

Effect of phloridzin on uric acid excretion in man

1 reference

12 December 2020

Renal metabolism of uric acid in type I insulin-dependent diabetic patients: relation to metabolic compensation

1 reference

12 December 2020

The metabolism of uric acid in the normal and gouty human studied with the aid of isotopic uric acid

1 reference

12 December 2020

Serum uric acid and cardiovascular events in successfully treated hypertensive patients

1 reference

12 December 2020

Identifiers

DOI

10.1002/BDD.1909

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

25044127

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json