(Q34470958)

English

Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386339%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types (English)

1 reference

Europe PubMed Central

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22 February 2020

Michael P Schwartz

8

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22 February 2020

author name string

Tyler D Hansen

1

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22 February 2020

Justin T Koepsel

2

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22 February 2020

Ngoc Nhi Le

3

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22 February 2020

Eric H Nguyen

4

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22 February 2020

Stefan Zorn

5

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22 February 2020

Matthew Parlato

6

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22 February 2020

Samuel G Loveland

7

1 reference

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22 February 2020

William L Murphy

9

1 reference

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22 February 2020

publication date

22 January 2014

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22 February 2020

Biomaterials Science

1 reference

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22 February 2020

2

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22 February 2020

5

1 reference

Europe PubMed Central

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22 February 2020

745-756

1 reference

Europe PubMed Central

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22 February 2020

A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Chemically well-defined self-assembled monolayers for cell culture: toward mimicking the natural ECM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Combinatorial screening of chemically defined human mesenchymal stem cell culture substrates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Three-dimensional photolithographic micropatterning: a novel tool to probe the complexities of cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Biophysical microenvironment and 3D culture physiological relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

A chemically-defined screening platform reveals behavioral similarities between primary human mesenchymal stem cells and endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Patterned self-assembled monolayers: efficient, chemically defined tools for cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Differential effects of a soluble or immobilized VEGFR-binding peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Nonpolarized signaling reveals two distinct modes of 3D cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Integrins in cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Bridging the gap between physicochemistry and interpretation prevalent in cell-surface interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Engineered 3D environments to elucidate the effect of environmental parameters on drug response in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Cancer cell stiffness: integrated roles of three-dimensional matrix stiffness and transforming potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

An inhibitor of a cell adhesion receptor stimulates cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Cancer dissemination--lessons from leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Can tissue engineering concepts advance tumor biology research?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Patterning discrete stem cell culture environments via localized self-assembled monolayer replacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Growth factors, matrices, and forces combine and control stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Specific roles of Rac1 and Rac2 in motile functions of HT1080 fibrosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Mechanical modes of 'amoeboid' cell migration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Using self-assembled monolayers to model the extracellular matrix.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Engineering tumors with 3D scaffolds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Differential roles of Rho-kinase and myosin light chain kinase in regulating shape, adhesion, and migration of HT1080 fibrosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Tumour-cell invasion and migration: diversity and escape mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Role of phosphoinositide 3-kinase in the aggressive tumor growth of HT1080 human fibrosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Dissection of Ras-dependent signaling pathways controlling aggressive tumor growth of human fibrosarcoma cells: evidence for a potential novel pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

RGD and other recognition sequences for integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Cell migration: a physically integrated molecular process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

The relationship of fibroblast translocations to cell morphology and stress fibre density.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Characterization of a newly derived human sarcoma cell line (HT-1080).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Mathematical model for the effects of adhesion and mechanics on cell migration speed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Inverse correlation between cell-surface adhesiveness and malignancy in mouse fibroblastoid cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

6 July 2018

Changes in integrin receptors on oncogenically transformed cells.

1 reference

https://api.crossref.org/works/10.1039%2FC3BM60278H

21 January 2018

Neutrophils display biphasic relationship between migration and substrate stiffness.

1 reference

https://api.crossref.org/works/10.1039%2FC3BM60278H

21 January 2018

Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion

1 reference

https://api.crossref.org/works/10.1039%2FC3BM60278H

21 January 2018

Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach

1 reference

https://api.crossref.org/works/10.1039%2FC3BM60278H

21 January 2018

A distinctive role for focal adhesion proteins in three-dimensional cell motility.

1 reference

https://api.crossref.org/works/10.1039%2FC3BM60278H

21 January 2018

Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224020

27 October 2018

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

1 reference

https://api.crossref.org/works/10.1039%2FC3BM60278H

21 January 2018

Neutrophil granulocytes: adhesion and locomotion on collagen substrata and in collagen matrices

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motility and adhesive properties of high- and low-metastatic murine neoplastic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of engineering approaches in analysing cancer invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion of metastatic and non-metastatic carcinoma cells to glass surfaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered organization of cell-substrate contacts and membrane-associated cytoskeleton in tumor cell variants exhibiting different metastatic capabilities

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How does the extracellular matrix direct gene expression?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25386339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1039/C3BM60278H

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386339%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386339%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386339%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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