(Q34471553)

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The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

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9 January 2020

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer (English)

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9 January 2020

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9 January 2020

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9 January 2020

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Robert Sewell

1

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9 January 2020

Malin Bäckström

2

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9 January 2020

Steven Gschmeissner

4

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9 January 2020

Hasse Karlsson

5

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9 January 2020

Thomas Noll

6

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9 January 2020

Jochem Gätgens

7

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9 January 2020

Henrik Clausen

8

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9 January 2020

Gunnar C Hansson

9

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9 January 2020

Joyce Taylor-Papadimitriou

11

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9 January 2020

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publication date

30 November 2005

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9 January 2020

number of pages

9

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Journal of Biological Chemistry

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281

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9 January 2020

6

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9 January 2020

3586-3594

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9 January 2020

describes a project that uses

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A genetic approach to Mammalian glycan function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

O-GlcNAc: a regulatory post-translational modification.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Carbohydrate-to-carbohydrate interaction in basic cell biology: a brief overview

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Glycosylation defining cancer malignancy: new wine in an old bottle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

O-linked glycosylation in the mammary gland: changes that occur during malignancy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-Golgi apparatus inhibits the development of core-2-based O-glycans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Biokinetics of yttrium-90--labeled huBrE-3 monoclonal antibody

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Expression of sialyl-Tn predicts the effect of adjuvant chemotherapy in node-positive breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

STn and prognosis in breast cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

A randomised phase II study of sialyl-Tn and DETOX-B adjuvant with or without cyclophosphamide pretreatment for the active specific immunotherapy of breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Bioprocess development for the production of a recombinant MUC1 fusion protein expressed by CHO-K1 cells in protein-free medium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Different modes of sialyl-Tn expression during malignant transformation of human colonic mucosa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Pathways of mucin O-glycosylation in normal and malignant rat colonic epithelial cells reveal a mechanism for cancer-associated Sialyl-Tn antigen expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

The lectin domain of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Expression of sialyl-Tn in gastric cancer: correlation with known prognostic factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4 transferase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511826200

21 January 2018

Identifiers

10.1074/JBC.M511826200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319059%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319059%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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