(Q34473649)

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Otx2 is involved in the regional specification of the developing retinal pigment epithelium by preventing the expression of sox2 and fgf8, factors that induce neural retina differentiation

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Otx2 is involved in the regional specification of the developing retinal pigment epithelium by preventing the expression of sox2 and fgf8, factors that induce neural retina differentiation (English)

1 reference

Europe PubMed Central

2 August 2017

author name string

Daisuke Nishihara

1

1 reference

Europe PubMed Central

2 August 2017

Ichiro Yajima

2

1 reference

Europe PubMed Central

2 August 2017

Hiromasa Tabata

3

1 reference

Europe PubMed Central

2 August 2017

Masato Nakai

4

1 reference

Europe PubMed Central

2 August 2017

Nagaharu Tsukiji

5

1 reference

Europe PubMed Central

2 August 2017

Tatsuya Katahira

6

1 reference

Europe PubMed Central

2 August 2017

Kazuhisa Takeda

7

1 reference

Europe PubMed Central

2 August 2017

Shigeki Shibahara

8

1 reference

Europe PubMed Central

2 August 2017

Harukazu Nakamura

9

1 reference

Europe PubMed Central

2 August 2017

Hiroaki Yamamoto

10

1 reference

Europe PubMed Central

2 August 2017

language of work or name

0 references

publication date

8 November 2012

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

7

1 reference

Europe PubMed Central

2 August 2017

11

1 reference

Europe PubMed Central

2 August 2017

e48879

1 reference

Europe PubMed Central

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development

1 reference

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6 July 2018

Eye morphogenesis and patterning of the optic vesicle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Ectopic Mitf in the embryonic chick retina by co-transfection of β-catenin and Otx2

1 reference

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6 July 2018

Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation

1 reference

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6 July 2018

Dual requirement for Pax6 in retinal progenitor cells

1 reference

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6 July 2018

Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation.

1 reference

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6 July 2018

Repression of Six3 by a corepressor regulates rhodopsin expression

1 reference

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6 July 2018

Retina regeneration in the chick embryo is not induced by spontaneous Mitf downregulation but requires FGF/FGFR/MEK/Erk dependent upregulation of Pax6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Eye development: a view from the retina pigmented epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

OTX2 activates the molecular network underlying retina pigment epithelium differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

OTX2 regulates expression of DOPAchrome tautomerase in human retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Activated MAPK/ERK kinase (MEK-1) induces transdifferentiation of pigmented epithelium into neural retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Dynamic domains of gene expression in the early avian forebrain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Pax6 is required for the multipotent state of retinal progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Six3 overexpression initiates the formation of ectopic retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Distributions of PAX6 and PAX7 proteins suggest their involvement in both early and late phases of chick brain development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Sequential expression and role of Hu RNA-binding proteins during neurogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Pax2 contributes to inner ear patterning and optic nerve trajectory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Multiple functions for Pax6 in mouse eye and nasal development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: implications for stepwise determination of the lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Basic fibroblast growth factor induces retinal pigment epithelium to generate neural retina in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Pax-6, a murine paired box gene, is expressed in the developing CNS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

Nested expression domains of four homeobox genes in developing rostral brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

6 July 2018

A series of normal stages in the development of the chick embryo. 1951

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

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Mitf functions as an in ovo regulator for cell differentiation and proliferation during development of the chick RPE.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

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Mouse Otx2 functions in the formation and patterning of rostral head.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Multiple functions of fibroblast growth factor-8 (FGF-8) in chick eye development

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Morphogenesis and cytodifferentiation of the avian retinal pigmented epithelium require downregulation of Group B1 Sox genes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Hu neuronal proteins are expressed in proliferating neurogenic cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Demarcation of ventral territories by the homeobox gene NKX2.1 during early chick development.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Development of dorsal-ventral polarity in the optic vesicle and its presumptive role in eye morphogenesis as shown by embryonic transplantation and in ovo explant culturing.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Extraocular dorsal signal affects the developmental fate of the optic vesicle and patterns the optic neuroepithelium

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Anteroventrally localized activity in the optic vesicle plays a crucial role in the optic development.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Generation of a second eye by embryonic transplantation of the antero-ventral hemicephalon.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Coordinated regulation of dorsal bone morphogenetic protein 4 and ventral Sonic hedgehog signaling specifies the dorso-ventral polarity in the optic vesicle and governs ocular morphogenesis through fibroblast growth factor 8 upregulation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048879

21 January 2018

Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

27 October 2018

Mosaics of islet-1-expressing amacrine cells assembled by short-range cellular interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

27 October 2018

Fibroblast growth factors are necessary for neural retina but not pigmented epithelium differentiation in chick embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

27 October 2018

Forebrain and midbrain regions are deleted in Otx2−/− mutants due to a defective anterior neuroectoderm specification during gastrulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493611

27 October 2018

Retinal fate and ganglion cell differentiation are potentiated by acidic FGF in an in vitro assay of early retinal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FGF1 patterns the optic vesicle by directing the placement of the neural retina domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dorsal retinal pigment epithelium differentiates as neural retina in the microphthalmia (mi/mi) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Otx genes are required for tissue specification in the developing eye

1 reference

https://pubmed.ncbi.nlm.nih.gov/23145006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0048879

1 reference

Europe PubMed Central

2 August 2017

2012PLoSO...748879N

0 references

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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