(Q34474341)

English

The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators.

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

apoptotic process

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Anne Chiaramello

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Martine Uittenbogaard

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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1 February 2005

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Journal of Neurochemistry

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

92

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

585-596

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry

1 reference

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6 July 2018

The basic helix-loop-helix differentiation factor Nex1/MATH-2 functions as a key activator of the GAP-43 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

The harlequin mouse mutation downregulates apoptosis-inducing factor

1 reference

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6 July 2018

Proneural genes and the specification of neural cell types

1 reference

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6 July 2018

Constitutive overexpression of the basic helix-loop-helix Nex1/MATH-2 transcription factor promotes neuronal differentiation of PC12 cells and neurite regeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

NF-kappaB in neuronal plasticity and neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Reciprocal developmental changes in the roles of Bcl-w and Bcl-x(L) in regulating sensory neuron survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Identification and characterization of nuclear factor kappaB binding sites in the murine bcl-x promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Phosphorylation of the PTEN tail regulates protein stability and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

The relationship between neuronal survival and regeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

CREB couples neurotrophin signals to survival messages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Generation of neurons by transient expression of neural bHLH proteins in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Cellular survival: a play in three Akts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Transcriptional analysis of human survivin gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

IAP family proteins--suppressors of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

hCDC47, a human member of the MCM family. Dissociation of the nucleus-bound form during S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Cell death during development of the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

6 July 2018

NEX-1: a novel brain-specific helix-loop-helix protein with autoregulation and sustained expression in mature cortical neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

A population of PC12 cells that is initiating apoptosis can be rescued by nerve growth factor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

Need for caspase-2 in apoptosis of growth-factor-deprived PC12 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

NeuroD2 is necessary for development and survival of central nervous system neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

Expression profiling upon Nex1/MATH-2-mediated neuritogenesis in PC12 cells and its implication in regeneration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

hCDC47, a Human Member of the MCM Family

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02886.X

21 January 2018

BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

27 October 2018

The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

27 October 2018

Neuronal basic helix-loop-helix proteins (NEX, neuroD, NDRF): spatiotemporal expression and targeted disruption of the NEX gene in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1411982

27 October 2018

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)-like activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor determines survival and death of PC12 cells by regulation of the bcl-x, bax, and caspase-3 genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation-dependent Akt cleavage in neural cell in vitro reconstitution of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 affects survival but not neuronal differentiation of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1471-4159.2004.02886.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659228%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

ResearchGate publication ID

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