(Q34475384)

2 August 2017

title

Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo (English)

1 reference

2 August 2017

Michael A Makara

1

1 reference

2 August 2017

Jerry Curran

2

1 reference

2 August 2017

Sean C Little

3

1 reference

2 August 2017

Hassan Musa

4

1 reference

2 August 2017

Iuliia Polina

5

1 reference

2 August 2017

Sakima A Smith

6

1 reference

2 August 2017

Patrick J Wright

7

1 reference

2 August 2017

Sathya D Unudurthi

8

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2 August 2017

Jed Snyder

9

1 reference

2 August 2017

Vann Bennett

10

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2 August 2017

Thomas J Hund

11

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2 August 2017

Peter J Mohler

12

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2 August 2017

publication date

19 September 2014

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2 August 2017

1 reference

2 August 2017

volume

115

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2 August 2017

issue

11

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2 August 2017

page(s)

929-938

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Nav channel complex heterogeneity: new targets for the treatment of arrhythmia?

2 August 2017

cites work

1 reference

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β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart.

6 July 2018

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Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype

6 July 2018

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βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells

6 July 2018

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Late sodium current inhibition: the most promising antiarrhythmic principle in the near future?

6 July 2018

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Mechanisms of altered Ca²⁺ handling in heart failure

6 July 2018

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Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

6 July 2018

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Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease

6 July 2018

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Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.

6 July 2018

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Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.

6 July 2018

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Genome-wide association study identifies five new schizophrenia loci

6 July 2018

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Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Interactions between ankyrin-G, Plakophilin-2, and Connexin43 at the cardiac intercalated disc

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac sodium channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory cilia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Roles and regulation of the cardiac sodium channel Na v 1.5: recent insights from experimental studies.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

A molecular defect in two families with hemolytic poikilocytic anemia: reduction of high affinity membrane binding sites for ankyrin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Mutations of ANK3 identified by exome sequencing are associated with autism susceptibility.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

Mutant beta-spectrin 4 causes auditory and motor neuropathies in quivering mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224970

BetaIV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier

27 October 2018

1 reference

12 December 2020

Deficient red-cell spectrin in severe, recessively inherited spherocytosis

1 reference

12 December 2020

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome

1 reference

12 December 2020

Spectrin- and ankyrin-based membrane domains and the evolution of vertebrates

1 reference

12 December 2020

10.1161/CIRCRESAHA.115.305154

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference