(Q34481154)

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TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-γ-mediated nitric oxide production

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-γ-mediated nitric oxide production (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Toxoplasma gondii

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author name string

Michael J Brumlik

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Srilakshmi Pandeswara

2

1 reference

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2 August 2017

Sara M Ludwig

3

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Europe PubMed Central

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2 August 2017

Duane P Jeansonne

4

1 reference

Europe PubMed Central

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2 August 2017

Michelle R Lacey

5

1 reference

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2 August 2017

Kruthi Murthy

6

1 reference

Europe PubMed Central

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2 August 2017

Benjamin J Daniel

7

1 reference

Europe PubMed Central

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2 August 2017

Rong-Fu Wang

8

1 reference

Europe PubMed Central

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2 August 2017

Suzanne R Thibodeaux

9

1 reference

Europe PubMed Central

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2 August 2017

Kristina M Church

10

1 reference

Europe PubMed Central

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2 August 2017

Vincent Hurez

11

1 reference

Europe PubMed Central

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2 August 2017

Mark J Kious

12

1 reference

Europe PubMed Central

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2 August 2017

Bin Zhang

13

1 reference

Europe PubMed Central

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2 August 2017

Adebusola Alagbala

14

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Europe PubMed Central

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2 August 2017

Xiaojun Xia

15

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Europe PubMed Central

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2 August 2017

Tyler J Curiel

16

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2 August 2017

publication date

27 March 2013

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2 August 2017

Experimental Parasitology

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2 August 2017

134

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2 August 2017

3

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Europe PubMed Central

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2 August 2017

389-399

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Europe PubMed Central

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2 August 2017

Parasite mitogen-activated protein kinases as drug discovery targets to treat human protozoan pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Toxoplasma gondii: epidemiology, feline clinical aspects, and prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

The TAK1-TRAF6 signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Kiss and spit: the dual roles of Toxoplasma rhoptries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Polymorphic secreted kinases are key virulence factors in toxoplasmosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Toxoplasma gondii prevents neuron degeneration by interferon-gamma-activated microglia in a mechanism involving inhibition of inducible nitric oxide synthase and transforming growth factor-beta1 production by infected microglia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

TRAF6-dependent mitogen-activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Toxoplasma gondii: the model apicomplexan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Heat shock protein 70 is a potential virulence factor in murine toxoplasma infection via immunomodulation of host NF-kappa B and nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Pyridinylimidazole p38 mitogen-activated protein kinase inhibitors block intracellular Toxoplasma gondii replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

L-tryptophan-L-kynurenine pathway metabolism accelerated by Toxoplasma gondii infection is abolished in gamma interferon-gene-deficient mice: cross-regulation between inducible nitric oxide synthase and indoleamine-2,3-dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

The role of gamma interferon in antimicrobial immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

p38 MAPK signalling cascades: ancient roles and new functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Consensus sequence of translational initiation sites from Toxoplasma gondii genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Role of macrophage-derived cytokines in the induction and regulation of cell-mediated immunity to Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Toxoplasmosis in the non-AIDS immunocompromised host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Cloned human CD4+ cytotoxic T lymphocytes specific for Toxoplasma gondii lyse tachyzoite-infected target cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Toxoplasmic encephalitis in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

6 July 2018

Toxoplasma gondii expresses two mitogen-activated protein kinase genes that represent distinct protozoan subfamilies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

27 October 2018

Identification of a novel mitogen-activated protein kinase in Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

27 October 2018

The mechanism of interferon-gamma induced anti Toxoplasma gondii by indoleamine 2,3-dioxygenase and/or inducible nitric oxide synthase vary among tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

27 October 2018

Phylogenetic and functional classification of mitogen- and stress-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

27 October 2018

Rapid isolation of DNA from trypanosomatid protozoa using a simple 'mini-prep' procedure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4226171

27 October 2018

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of the inducible nitric oxide synthase after infection with Toxoplasma gondii facilitates parasite replication in activated murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxoplasma gondii partially inhibits nitric oxide production of activated murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical expression of inducible nitric oxide synthase (iNOS) in reversible endotoxic shock studied by a novel monoclonal antibody against rat iNOS

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the expression of nitric oxide synthase by Leishmania mexicana amastigotes in murine dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23541881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPPARA.2013.03.016

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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