(Q34481618)

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Non-nucleoside reverse transcriptase inhibitors: perspectives on novel therapeutic compounds and strategies for the treatment of HIV infection

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Europe PubMed Central

Non-nucleoside reverse transcriptase inhibitors: perspectives on novel therapeutic compounds and strategies for the treatment of HIV infection (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Buckheit RW

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

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publication date

1 August 2001

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Europe PubMed Central

PubMed publication ID

2 August 2017

Expert Opinion on Investigational Drugs

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Europe PubMed Central

PubMed publication ID

2 August 2017

10

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Europe PubMed Central

PubMed publication ID

2 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1423-1442

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Delavirdine: clinical pharmacokinetics and drug interactions

1 reference

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Nevirapine: a review of its use in the prevention and treatment of paediatric HIV infection

1 reference

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Novel compounds in preclinical/early clinical development for the treatment of HIV infections

1 reference

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21 January 2018

The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.

1 reference

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21 January 2018

Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection

1 reference

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21 January 2018

The emerging roles of non-nucleoside reverse transcriptase inhibitors in antiretroviral therapy

1 reference

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Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

1 reference

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21 January 2018

Novel 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine derivatives as non-nucleoside reverse transcriptase inhibitors that inhibit human immunodeficiency virus type 1 replication

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21 January 2018

Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus

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21 January 2018

Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus

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5-Alkyl-2-[(methylthiomethyl)thio]-6-(benzyl)-pyrimidin-4-(1H)-ones as potent non-nucleoside reverse transcriptase inhibitors of S-DABO series

1 reference

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21 January 2018

HIV resistance to reverse transcriptase inhibitors

1 reference

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21 January 2018

Nonnucleoside inhibitors of HIV-1 reverse transcriptase: nevirapine as a prototype drug

1 reference

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21 January 2018

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

1 reference

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21 January 2018

HIV reverse transcriptase structure-function relationships

1 reference

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21 January 2018

HIV-1 Reverse Transcriptase: Structure Predictions for the Polymerase Domain

1 reference

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21 January 2018

Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV

1 reference

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Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase

1 reference

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21 January 2018

Thiazolobenzimidazole: biological and biochemical anti-retroviral activity of a new nonnucleoside reverse transcriptase inhibitor

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21 January 2018

Structure-activity and cross-resistance evaluations of a series of human immunodeficiency virus type-1-specific compounds related to oxathiin carboxanilide

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21 January 2018

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

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21 January 2018

Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds

1 reference

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21 January 2018

Carboxanilide derivative non-nucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme

1 reference

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21 January 2018

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

1 reference

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21 January 2018

Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1.

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21 January 2018

Preclinical studies on thiocarboxanilide UC-781 as a virucidal agent.

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A novel mutation (F227L) arises in the reverse transcriptase of human immunodeficiency virus type 1 on dose-escalating treatment of HIV type 1-infected cell cultures with the nonnucleoside reverse transcriptase inhibitor thiocarboxanilide UC-781.

1 reference

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21 January 2018

The role of genotypic heterogeneity in wild type virus populations on the selection of nonnucleoside reverse transcriptase inhibitor-resistant viruses

1 reference

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21 January 2018

Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial

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Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus

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21 January 2018

Identifiers

10.1517/13543784.10.8.1423

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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