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English
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
title
Purmorphamine activates the Hedgehog pathway by targeting Smoothened
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
main subject
purmorphamine
1 reference
stated in
ChEBI release 2020-05-28
ChEBI ID
63053
author
James K. Chen
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author name string
Surajit Sinha
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
publication date
20 November 2005
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
published in
Nature Chemical Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
volume
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
page(s)
29-30
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
cites work
Hedgehog signaling in animal development: paradigms and principles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue repair and stem cell renewal in carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental roles and clinical significance of hedgehog signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small molecule modulation of Smoothened activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCHEMBIO753
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NCHEMBIO753
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PubMed publication ID
16408088
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16408088
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16408088%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
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