(Q34485808)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility (English)

1 reference

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13 February 2020

7

1 reference

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13 February 2020

Gopal J Babu

8

1 reference

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13 February 2020

author name string

Mayilvahanan Shanmugam

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Shumin Gao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Chull Hong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Nadezhda Fefelova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Martha C Nowycky

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Lai-Hua Xie

6

1 reference

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13 February 2020

publication date

10 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

published in

Cardiovascular Research

1 reference

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13 February 2020

volume

89

1 reference

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13 February 2020

issue

2

1 reference

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13 February 2020

page(s)

353-361

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

PI3K kinase and scaffold functions in heart.

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Oxidative-stress-induced afterdepolarizations and calmodulin kinase II signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Reversing advanced heart failure by targeting Ca2+ cycling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

The Ca2+ ATPase of cardiac sarcoplasmic reticulum: Physiological role and relevance to diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Regulation of sarcoplasmic reticulum Ca2+ ATPase pump expression and its relevance to cardiac muscle physiology and pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Ablation of sarcolipin enhances sarcoplasmic reticulum calcium transport and atrial contractility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Sarcolipin and phospholamban as regulators of cardiac sarcoplasmic reticulum Ca2+ ATPase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

New perspectives on the role of SERCA2's Ca2+ affinity in cardiac function.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Molecular aspects of adrenergic modulation of cardiac L-type Ca2+ channels.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Altered cardiac calcium handling in diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Cardiac ryanodine receptor function and regulation in heart disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Phospholamban: a crucial regulator of cardiac contractility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Modulation of SERCA: implications for the failing human heart.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Targeting phospholamban by gene transfer in human heart failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Phospholamban deficiency alters inactivation kinetics of L-type Ca2+ channels in mouse ventricular myocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Compensatory mechanisms associated with the hyperdynamic function of phospholamban-deficient mouse hearts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020129

Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Reduced contraction strength with increased intracellular [Ca2+] in left ventricular trabeculae from failing rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Disruption of type 5 adenylyl cyclase enhances desensitization of cyclic adenosine monophosphate signal and increases Akt signal with chronic catecholamine stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Selective activation of PI3Kalpha/Akt/GSK-3beta signalling and cardiac compensatory hypertrophy during recovery from heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ294

Down-regulation of sarcolipin mRNA expression in chronic atrial fibrillation

21 January 2018

1 reference

12 December 2020

Akt1 is required for physiological cardiac growth

1 reference

12 December 2020

A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span

1 reference

12 December 2020

Mechanisms of excitation-contraction coupling failure during metabolic inhibition in guinea-pig ventricular myocytes.

1 reference

12 December 2020

Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium

1 reference

12 December 2020

In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency

1 reference

12 December 2020

Identifiers

DOI

10.1093/CVR/CVQ294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833651%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20833651

1 reference