(Q34487585)

2 August 2017

Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1. (English)

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2 August 2017

1 reference

Yuanzhang Fang

1

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2 August 2017

Yihua Chen

2

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2 August 2017

Linxi Yu

3

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2 August 2017

Cong Zheng

4

1 reference

2 August 2017

Ya Qi

5

1 reference

2 August 2017

Zhenxi Li

6

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2 August 2017

Zhengfeng Yang

7

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2 August 2017

Yong Zhang

8

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2 August 2017

Tieliu Shi

9

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2 August 2017

Jian Luo

10

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2 August 2017

Mingyao Liu

11

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2 August 2017

language of work or name

English

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publication date

24 November 2012

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Journal of the National Cancer Institute

2 August 2017

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2 August 2017

105

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2 August 2017

1

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2 August 2017

47-58

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2 August 2017

Global cancer statistics

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https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Breast cancer metastasis to bone: it is not all about PTHrP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Roles of TGFbeta in metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGF-beta receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGF-beta1 in myelo-monocytic leukaemic cells co-cultured with stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Targeting the transforming growth factor-beta signaling pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

The notch and TGF-β signaling pathways contribute to the aggressiveness of clear cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Metabolism, excretion, and pharmacokinetics of [14C]INCB018424, a selective Janus tyrosine kinase 1/2 inhibitor, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Pharmacological inhibition of transforming growth factor beta signaling decreases infection and prevents heart damage in acute Chagas' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Connective tissue growth factor induction by lysophosphatidic acid requires transactivation of transforming growth factor type β receptors and the JNK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Improvement of the breaking strength of wound by combined treatment with recombinant human G-CSF, recombinant human M-CSF, and a TGF-beta1 receptor kinase inhibitor in rat skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Plumbagin inhibits breast tumor bone metastasis and osteolysis by modulating the tumor-bone microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Genes that mediate breast cancer metastasis to lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Design, synthesis and biological activity of new CDK4-specific inhibitors, based on fascaplysin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Inhibitors of the TGF-beta superfamily and their clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJS485

21 January 2018

Identifiers

DOI

10.1093/JNCI/DJS485

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2 August 2017

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