(Q34489094)

2 August 2017

title

The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction. (English)

1 reference

2 August 2017

Sangeeta Adak

1

1 reference

2 August 2017

Diana DeAndrade

series ordinal

2

1 reference

2 August 2017

Linda J Pike

series ordinal

3

1 reference

2 August 2017

language of work or name

English

0 references

publication date

3 November 2010

1 reference

Journal of Biological Chemistry

2 August 2017

published in

1 reference

2 August 2017

volume

286

1 reference

2 August 2017

issue

2

1 reference

2 August 2017

page(s)

1545-1555

1 reference

Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

2 August 2017

cites work

1 reference

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ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor

6 July 2018

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6 July 2018

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

6 July 2018

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Functional and structural stability of the epidermal growth factor receptor in detergent micelles and phospholipid nanodiscs.

6 July 2018

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Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system

6 July 2018

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6 July 2018

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Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

6 July 2018

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Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis

6 July 2018

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CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

6 July 2018

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The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function

6 July 2018

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6 July 2018

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

6 July 2018

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The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

6 July 2018

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Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

6 July 2018

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

6 July 2018

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Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

6 July 2018

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Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Second cysteine-rich region of epidermal growth factor receptor contains targeting information for caveolae/rafts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

6 July 2018

1 reference

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Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Interaction of the extracellular domain of the epidermal growth factor receptor with gangliosides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Untangling the ErbB signalling network

6 July 2018

1 reference

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The ErbB signaling network: receptor heterodimerization in development and cancer

6 July 2018

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Regulated migration of epidermal growth factor receptor from caveolae

6 July 2018

1 reference

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Mutagenesis reveals a role for epidermal growth factor receptor extracellular subdomain IV in ligand binding

6 July 2018

1 reference

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Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover

6 July 2018

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Activation of the EGF receptor by insertional mutations in its juxtamembrane regions.

6 July 2018

1 reference

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Oxidative iodine monochloride iodination technique

6 July 2018

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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

6 July 2018

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High affinity epidermal growth factor receptors on the surface of A431 cells have restricted lateral diffusion

6 July 2018

1 reference

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On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.

6 July 2018

1 reference

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Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Localization of a major receptor-binding domain for epidermal growth factor by affinity labeling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020763

Ectodomain orientation, conformational plasticity and oligomerization of ErbB1 receptors investigated by molecular dynamics.

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

Ligand-induced structural transitions in ErbB receptor extracellular domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

A simplified method for the preparation of detergent-free lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

Ganglioside depletion and EGF responses of human GM3 synthase-deficient fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

Ganglioside modulates ligand binding to the epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.182899

Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21047778

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21047778

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21047778

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.182899

1 reference

2 August 2017

1 reference

2 August 2017

1 reference