(Q34492884)

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A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Yingting Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Jeremy Purvis

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Andrew Shih

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Joshua Weinstein

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Neeraj Agrawal

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Ravi Radhakrishnan

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

2 February 2007

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Annals of Biomedical Engineering

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

35

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1012-1025

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Collecting and organizing systematic sets of protein data

1 reference

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Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

1 reference

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EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer

1 reference

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6 July 2018

Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib

1 reference

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EGF-ERBB signalling: towards the systems level

1 reference

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An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

1 reference

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1 reference

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A biological approach to computational models of proteomic networks

1 reference

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1 reference

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1 reference

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Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions

1 reference

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EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

1 reference

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A small molecule-kinase interaction map for clinical kinase inhibitors

1 reference

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Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255.

1 reference

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A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

1 reference

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6 July 2018

Regulation of protein kinases; controlling activity through activation segment conformation

1 reference

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6 July 2018

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

1 reference

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6 July 2018

Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites

1 reference

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6 July 2018

Predictive factors for epidermal growth factor receptor inhibitors--the bull's-eye hits the arrow

1 reference

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6 July 2018

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021414

6 July 2018

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

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The role of EGFR inhibitors in nonsmall cell lung cancer

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Challenges in the development of anti-epidermal growth factor receptor therapies in breast cancer

1 reference

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6 July 2018

Epidermal growth factor receptor inhibitors in clinical development

1 reference

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6 July 2018

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

1 reference

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6 July 2018

Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathwa

1 reference

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6 July 2018

Epidermal growth factor receptor: mechanisms of activation and signalling.

1 reference

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The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors

1 reference

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

1 reference

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Cancer drugs. Smart weapons prove tough to design

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Curvature of clathrin-coated pits driven by epsin

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Epidermal growth factor receptor dependence in human tumors: more than just expression?

1 reference

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6 July 2018

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

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6 July 2018

Smart drugs: tyrosine kinase inhibitors in cancer therapy

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6 July 2018

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

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The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

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Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

1 reference

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Untangling the ErbB signalling network

1 reference

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Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases

1 reference

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Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents

1 reference

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Cell signaling by receptor tyrosine kinases

1 reference

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Protein tyrosine kinase structure and function

1 reference

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Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.

1 reference

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Strategies toward the design of novel and selective protein tyrosine kinase inhibitors

1 reference

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1 reference

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Ruthenium complexes as protein kinase inhibitors.

1 reference

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1 reference

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A unified polymerase mechanism for nonhomologous DNA and RNA polymerases

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential inhibition of epidermal growth factor signaling pathways in rat hepatocytes by long-term ethanol treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17273938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17273938

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The statistical mechanics of complex signaling networks: nerve growth factor signaling

1 reference

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Identifiers

10.1007/S10439-006-9251-0

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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