(Q34493922)

English

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Stephen M. Hewitt

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Michael P. O'Connell

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

Tura C Camilli

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Mai Xu

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Bonnie Chien

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Brittany P Frank

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Sarah Subaran

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Fred E Indig

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Patrice J Morin

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Ashani T Weeraratna

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

publication date

1 December 2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Pigment Cell & Melanoma Research

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

24

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

175-186

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Wnt5A activates the calpain-mediated cleavage of filamin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

WNT5A expression increases during melanoma progression and correlates with outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Augmented Wnt signaling in a mammalian model of accelerated aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Cellular senescence: when bad things happen to good cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Regulation of fibroblast growth factor-23 signaling by klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Opticin binds to heparan and chondroitin sulfate proteoglycans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Suppression of aging in mice by the hormone Klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Klotho is a serum factor related to human aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Sialidase and malignancy: a minireview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Is the senescent heart overloaded and already failing?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Low levels of calpain activity in Chiroptera brain: implications for mechanisms of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

6 July 2018

Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00792.X

21 January 2018

Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00792.X

21 January 2018

Human sialidase as a cancer marker

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00792.X

21 January 2018

Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00792.X

21 January 2018

Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00792.X

21 January 2018

Decreased G-protein-mediated regulation and shift in calcium channel types with age in hippocampal cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

27 October 2018

Differential modulation of synaptic transmission by calcium chelators in young and aged hippocampal CA1 neurons: evidence for altered calcium homeostasis in aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021583

27 October 2018

Klotho protein deficiency leads to overactivation of mu-calpain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20955350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium pump phosphoenzyme from young and old human red cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20955350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An endogenous Ca2+-sensitive proteinase converts the hepatic alpha 1-adrenergic receptor to guanine nucleotide-insensitive forms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20955350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward a better understanding of Klotho

1 reference

https://pubmed.ncbi.nlm.nih.gov/20955350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiologic Support for Melanoma Heterogeneity Using the Surveillance, Epidemiology, and End Results Program

1 reference

https://pubmed.ncbi.nlm.nih.gov/20955350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1755-148X.2010.00792.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955350%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34493922&oldid=1599288331"