(Q34496406)

2 August 2017

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title

Microenvironmental niches in the bone marrow required for B-cell development (English)

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2 August 2017

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Takashi Nagasawa

1

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2 August 2017

1 February 2006

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Nature Reviews Immunology

2 August 2017

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2 August 2017

6

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2 August 2017

107-116

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2 August 2017

2

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Microenvironmental organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow

2 August 2017

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Endosteal marrow: a rich source of hematopoietic stem cells

21 January 2018

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Osteoblastic cells regulate the haematopoietic stem cell niche

21 January 2018

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Identification of the haematopoietic stem cell niche and control of the niche size

21 January 2018

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A developing picture of lymphopoiesis in bone marrow

21 January 2018

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Cellular niches controlling B lymphocyte behavior within bone marrow during development.

21 January 2018

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Lifetime of plasma cells in the bone marrow.

21 January 2018

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

21 January 2018

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Commitment to the B lymphoid lineage occurs before DH-JH recombination

21 January 2018

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Early B-cell development in the mouse: insights from mutations introduced by gene targeting

21 January 2018

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Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential.

21 January 2018

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A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors

21 January 2018

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Characterization of distinct conventional and plasmacytoid dendritic cell-committed precursors in murine bone marrow.

21 January 2018

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Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow

21 January 2018

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

21 January 2018

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Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

21 January 2018

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Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

21 January 2018

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

21 January 2018

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A common pathway for dendritic cell and early B cell development.

21 January 2018

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Bipotential B-macrophage progenitors are present in adult bone marrow.

21 January 2018

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Long-term culture of B lymphocytes and their precursors from murine bone marrow

21 January 2018

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A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells

21 January 2018

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Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule.

21 January 2018

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The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-B cell growth-stimulating factor.

21 January 2018

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Human chemokines: an update

21 January 2018

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Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins

21 January 2018

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Molecular cloning and structure of a pre-B-cell growth-stimulating factor

21 January 2018

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

21 January 2018

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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

21 January 2018

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The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

21 January 2018

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

21 January 2018

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The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4.

21 January 2018

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The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity

21 January 2018

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A coordinated change in chemokine responsiveness guides plasma cell movements

21 January 2018

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A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitution

21 January 2018

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A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo

21 January 2018

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Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

21 January 2018

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Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

21 January 2018

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A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

21 January 2018

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Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

21 January 2018

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Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

21 January 2018

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Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

21 January 2018

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Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

21 January 2018

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Notch signaling controls the generation and differentiation of early T lineage progenitors

21 January 2018

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Stimulation of B-cell progenitors by cloned murine interleukin-7

21 January 2018

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

21 January 2018

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Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

21 January 2018

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Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

21 January 2018

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Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 January 2018

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Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

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Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice

21 January 2018

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Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors

21 January 2018

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Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

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Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor

21 January 2018

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Failure of B-cell differentiation in mice lacking the transcription factor EBF.

21 January 2018

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IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF.

21 January 2018

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Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development

21 January 2018

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A role for thymic stromal lymphopoietin in CD4(+) T cell development

21 January 2018

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Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development

21 January 2018

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Primary structure and functional expression of rat and human stem cell factor DNAs

21 January 2018

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The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

21 January 2018

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Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

21 January 2018

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Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis

21 January 2018

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Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region.

21 January 2018

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

21 January 2018

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

21 January 2018

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

21 January 2018

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A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

21 January 2018

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RANK is essential for osteoclast and lymph node development

21 January 2018

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The hematopoietic microenvironment of the bone marrow: an ultrastructural study of the stroma in rats

21 January 2018

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Cultured mouse marrow stromal cell lines. II. Distinct subtypes differing in morphology, collagen types, myelopoietic factors, and leukemic cell growth modulating activities

21 January 2018

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Interleukin 7 production and function in stromal cell-dependent B cell development

21 January 2018

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Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche

21 January 2018

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Hematopoiesis is severely altered in mice with an induced osteoblast deficiency

21 January 2018

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Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

21 January 2018

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G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

21 January 2018

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G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

21 January 2018

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Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.

21 January 2018

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Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific, IgG1+ B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP.

21 January 2018

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Precursor B cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment

21 January 2018

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

21 January 2018

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Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

21 January 2018

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Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches

21 January 2018

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Identification of the earliest B lineage stage in mouse bone marrow

31 March 2020

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Functional assessment of precursors from murine bone marrow suggests a sequence of early B lineage differentiation events

31 March 2020

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Phenotypic distinction and functional characterization of pro-B cells in adult mouse bone marrow

31 March 2020

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Thymopoiesis independent of common lymphoid progenitors

31 March 2020

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Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny

31 March 2020

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The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment

31 March 2020

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Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs

31 March 2020

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Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

31 March 2020

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Defective lymphoid development in mice lacking Jak3

31 March 2020

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B lymphocytes express and lose syndecan at specific stages of differentiation

31 March 2020

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Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI1780

1 reference

2 August 2017

1 reference

PubMed ID

16491135