(Q34496489)

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Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Zheng-Gen Jin

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Chelsea Wong

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Jie Wu

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Bradford C Berk

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

0 references

publication date

21 January 2005

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

12305-12309

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

VEGF signalling: integration and multi-tasking in endothelial cell biology

1 reference

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7 July 2018

The "Gab" in signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Signal transduction by vascular endothelial growth factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

The gift of Gab.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Essential role for Gab2 in the allergic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Anti-inflammatory mechanisms in the vascular wall.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Cell signaling by receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Essential role of Gab1 for signaling by the c-Met receptor in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Endothelial dysfunction, hemodynamic forces, and atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Signaling through scaffold, anchoring, and adaptor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Endothelial vasodilator dysfunction: pathogenetic link to myocardial ischaemia or epiphenomenon?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Phosphorylation and subcellular translocation of endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Flow-mediated endothelial mechanotransduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

7 July 2018

Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500294200

21 January 2018

Cyclophilin A is a proinflammatory cytokine that activates endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500294200

21 January 2018

Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500294200

21 January 2018

Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228934

27 October 2018

Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin A is a secreted growth factor induced by oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flow-induced release of endothelium-derived relaxing factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/15665327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M500294200

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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