(Q34500928)

2 August 2017

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title

Immunology of viral-vector-mediated gene transfer into the brain: an evolutionary and developmental perspective (English)

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2 August 2017

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Pedro R Lowenstein

1

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2 August 2017

publication date

1 January 2002

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2 August 2017

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2 August 2017

volume

23

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2 August 2017

issue

1

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2 August 2017

page(s)

23-30

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The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme

2 August 2017

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Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

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Immune responses to adenovirus vectors in the nervous system

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A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain.

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

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Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain.

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Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

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7 January 2021

Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system

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7 January 2021

The role of chemokine receptors in primary, effector, and memory immune responses

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7 January 2021

The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissues

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7 January 2021

Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation

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7 January 2021

A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation.

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7 January 2021

The immunogenicity of intracerebral virus infection depends on anatomical site.

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7 January 2021

Migratory Activity and Functional Changes of Green Fluorescent Effector Cells before and during Experimental Autoimmune Encephalomyelitis

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7 January 2021

An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy

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7 January 2021

Complement components of the innate immune system in health and disease in the CNS.

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7 January 2021

CONDITIONS DETERMINING THE TRANSPLANTABILITY OF TISSUES IN THE BRAIN.

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7 January 2021

Dendritic cells and the control of immunity

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7 January 2021

Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis

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7 January 2021

Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

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7 January 2021

Brain dendritic cells and macrophages/microglia in central nervous system inflammation.

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Churchill and the immune system of ectothermic vertebrates

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Innate immune recognition: mechanisms and pathways

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7 January 2021

Developmental plasticity of CNS microglia

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7 January 2021

Do lampreys have lymphocytes? The Spi evidence

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7 January 2021

Lymphocytes and macrophages outnumber oligodendroglia in normal fish spinal cord

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7 January 2021

Innate and adaptive immune responses can be beneficial for CNS repair

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7 January 2021

The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis.

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7 January 2021

Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

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7 January 2021

The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous system.

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7 January 2021

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

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7 January 2021

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

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7 January 2021

Disproportionate recruitment of CD8+ T cells into the central nervous system by professional antigen-presenting cells

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7 January 2021

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors

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7 January 2021

Classification of demyelinating diseases at the interface between etiology and pathogenesis.

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7 January 2021

Genetic models for CNS inflammation

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7 January 2021

Basic concepts of immunology and neuroimmunology

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7 January 2021

10.1016/S1471-4906(01)02063-4

Identifiers

DOI

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2 August 2017

1 reference