(Q34501451)

2 August 2017

title

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice (English)

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2 August 2017

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Patrizia Nigro

1

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2 August 2017

Kimio Satoh

2

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2 August 2017

Michael R O'Dell

3

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2 August 2017

Nwe Nwe Soe

4

1 reference

2 August 2017

Zhaoqiang Cui

5

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2 August 2017

Amy Mohan

6

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2 August 2017

Jun-ichi Abe

7

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2 August 2017

Jeffrey D Alexis

8

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2 August 2017

Janet D Sparks

9

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2 August 2017

Bradford C Berk

10

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2 August 2017

language of work or name

English

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publication date

20 December 2010

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Journal of Experimental Medicine

2 August 2017

published in

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2 August 2017

volume

208

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2 August 2017

issue

1

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2 August 2017

page(s)

53-66

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Cyclosporin A and atherosclerosis--cellular pathways in atherogenesis

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Prevention of atherosclerosis by interference with the vascular nitric oxide system

7 July 2018

1 reference

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Understanding abdominal aortic aneurysm

7 July 2018

1 reference

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Immune and inflammatory mechanisms of atherosclerosis (*)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Cyclophilin A is required for CXCR4-mediated nuclear export of heterogeneous nuclear ribonucleoprotein A2, activation and nuclear translocation of ERK1/2, and chemotactic cell migration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Role of Krüppel-like transcription factors in endothelial biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

The immune response in atherosclerosis: a double-edged sword

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Extracellular cyclophilins contribute to the regulation of inflammatory responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Inflammation, atherosclerosis, and coronary artery disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Dysfunction of endothelial nitric oxide synthase and atherosclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Active site residues of cyclophilin A are crucial for its signaling activity via CD147

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Influence of caveolin, cholesterol, and lipoproteins on nitric oxide synthase: implications for vascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

A major role for VCAM-1, but not ICAM-1, in early atherosclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Atherosclerosis. the road ahead

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Endothelial NO synthase overexpression inhibits lesion formation in mouse model of vascular remodeling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Effect of cyclosporine on HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, HDL receptor, VLDL receptor, and lipoprotein lipase expressions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Hemizygous deficiency of Krüppel-like factor 2 augments experimental atherosclerosis

7 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cyclophilin A is a proinflammatory cytokine that activates endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cardiovascular complications after renal transplantation and their prevention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101174

Glucose-stimulated insulin secretion suppresses hepatic triglyceride-rich lipoprotein and apoB production.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023134

Cyclophilin A is a secreted growth factor induced by oxidative stress

27 October 2018

1 reference

12 December 2020

Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice

1 reference

12 December 2020

Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein e/endothelial nitric oxide synthase double knockout mice

1 reference

12 December 2020

Leukocyte chemotactic activity of cyclophilin

1 reference

12 December 2020

Low-density lipoprotein metabolism in rats treated with cyclosporine

1 reference

12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

12 December 2020

Elevated serum cyclophilin levels in patients with severe sepsis

1 reference

12 December 2020

Lipid abnormalities in stable liver transplant recipients--effects of cyclosporin, tacrolimus, and steroids

1 reference

12 December 2020

Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse

1 reference

12 December 2020

EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation

1 reference

12 December 2020

Region-specific patterns of vascular remodelling occur early in atherosclerosis and without loss of smooth muscle cell markers

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20101174

1 reference

2 August 2017

1 reference

2 August 2017

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