(Q34505121)

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Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail

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Europe PubMed Central

PubMed publication ID

2 August 2017

Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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author name string

C Nakaseko

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

S Miyatake

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

T Iida

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

S Hara

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

R Abe

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

H Ohno

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Y Saito

7

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

T Saito

8

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

1 September 1999

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Europe PubMed Central

PubMed publication ID

2 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

PubMed publication ID

2 August 2017

190

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

765-774

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Molecular basis of T cell inactivation by CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Interaction of the cytoplasmic tail of CTLA-4 (CD152) with a clathrin-associated protein is negatively regulated by tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Association with FcRgamma is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

The emerging role of CTLA-4 as an immune attenuator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

A new 12-kilodalton dimer associated with pre-TCR complex and clonotype-independent CD3 complex on immature thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Co-stimulation in T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CTLA-4 ligation blocks CD28-dependent T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Upstream-downstream: CD28 cosignaling pathways and T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Applications of retrovirus-mediated expression cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CTLA-4 can function as a negative regulator of T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

7 July 2018

Negative regulation of T cell activation

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice

2 references

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

27 October 2018

CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

27 October 2018

Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

27 October 2018

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

27 October 2018

Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

27 October 2018

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195638

27 October 2018

Human Influence on the Atmospheric Vertical Temperature Structure: Detection and Observations

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

Epitopes associated with major histocompatibility complex (MHC) restriction site of T cells. IV. I-J epitopes on MHC-restricted cloned T cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

Induction of interleukin-2 unresponsiveness and down-regulation of the JAK-STAT system upon activation through the T cell receptor

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.6.765

21 January 2018

Identifiers

10.1084/JEM.190.6.765

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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