(Q34508455)

2 August 2017

1 reference

title

Metronidazole resistance in Helicobacter pylori. (English)

1 reference

Helicobacter pylori infectious disease

2 August 2017

0 references

1 reference

1 reference

Peter J Jenks

1

1 reference

PubMed ID

11814762

2 August 2017

David I Edwards

series ordinal

2

1 reference

2 August 2017

1 January 2002

1 reference

International Journal of Antimicrobial Agents

2 August 2017

1 reference

2 August 2017

19

1 reference

2 August 2017

1-7

1 reference

2 August 2017

1

1 reference

Helicobacter pylori infection and the risk of gastric carcinoma

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Helicobacter pylori: microbiology of a 'slow' bacterial infection

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Helicobacter pylori infection and gastric lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole resistance reduces efficacy of triple therapy and leads to secondary clarithromycin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Antibiotic resistance in Helicobacter pylori: implications for therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Exposure to metronidazole in vivo readily induces resistance in Helicobacter pylori and reduces the efficacy of eradication therapy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Evaluation of nitrofurantoin combination therapy of metronidazole-sensitive and -resistant Helicobacter pylori infections in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

A systematic review of Helicobacter pylori eradication therapy--the impact of antimicrobial resistance on eradication rates

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy: a meta-analytical approach

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The influence of in vitro nitroimidazole resistance on the efficacy of nitroimidazole-containing anti-Helicobacter pylori regimens: a meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Evolution of resistance to metronidazole and clarithromycin in Helicobacter pylori clinical isolates from Spain

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Rapid increase in the prevalence of metronidazole-resistant Helicobacter pylori in the Netherlands

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Absorption, tissue concentration, and organ distribution of cefazolin

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Redox potential and oxygen concentration as factors in the susceptibility of Helicobacter pylori to nitroheterocyclic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The selective toxicity of antimicrobial nitroheterocyclic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Nitroimidazole drugs-action and resistance mechanisms I. Mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The mode of action of metronidazole in Trichomonas vaginalis and other micro-organisms

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Distribution of metronidazole susceptibility factors in obligate anaerobes

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Nitroimidazole drugs--action and resistance mechanisms. II. Mechanisms of resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Characterisation and purification of pyruvate:ferredoxin oxidoreductase from Giardia duodenalis

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole resistance in the protozoan parasite Entamoeba histolytica is associated with increased expression of iron-containing superoxide dismutase and peroxiredoxin and decreased expression of ferredoxin 1 and flavin reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Involvement of superoxide dismutase and pyruvate:ferredoxin oxidoreductase in mechanisms of metronidazole resistance in Entamoeba histolytica

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole uptake by sensitive and resistant isolates of Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The mode of action of metronidazole in Helicobacter pylori: futile cycling or reduction?

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Proposed mechanism for metronidazole resistance in Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The influence of microaerophilia and anaerobiosis on metronidazole uptake in Helicobacter pylori.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole-resistant clinical isolates of Trichomonas vaginalis have lowered oxygen affinities.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole resistance and microaerophily in Campylobacter species

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Oxygen scavenging, NADH oxidase and metronidazole resistance in Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Identification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Flavodoxin-dependent pyruvate oxidation, acetate production and metronidazole reduction by Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Helicobacter pylori porCDAB and oorDABC genes encode distinct pyruvate:flavodoxin and 2-oxoglutarate:acceptor oxidoreductases which mediate electron transport to NADP

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The complete genome sequence of the gastric pathogen Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Frequent association between alteration of the rdxA gene and metronidazole resistance in French and North African isolates of Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

The role of the rdxA gene in the evolution of metronidazole resistance in Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Frameshift mutations in rdxA and metronidazole resistance in North American Helicobacter pylori isolates.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Mechanism of metronidazole resistance in Helicobacter pylori: comparison of the rdxA gene sequences in 30 strains

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Spontaneous mutations that confer antibiotic resistance in Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Frame-shift mutations in NAD(P)H flavin oxidoreductase encoding gene (frxA) from metronidazole resistant Helicobacter pylori ATCC43504 and its involvement in metronidazole resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Mouse-colonizing Helicobacter pylori SS1 is unusually susceptible to metronidazole due to two complementary reductase activities

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Isolation of a genetic locus associated with metronidazole resistance in Helicobacter pylori.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Helicobacter pylori uptake and efflux: basis for intrinsic susceptibility to antibiotics in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Review article: nitroimidazole resistance in Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Targeted disruption of the gene encoding the classical nitroreductase enzyme in Salmonella typhimurium Ames test strains TA1535 and TA1538.

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Electrochemical characteristics of nitroheterocyclic compounds of biological interest. VIII. Stability of nitro radical anions from cyclic voltammetric studies

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

1 reference

7 January 2021

Metronidazole and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Prenatal exposure to metronidazole and risk of childhood cancer: a retrospective cohort study of children younger than 5 years

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Reinvestigation of in vivo genotoxicity studies in man. I. No induction of DNA strand breaks in peripheral lymphocytes after metronidazole therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Short-term infection with Helicobacter pylori and 1 week exposure to metronidazole does not enhance gastric mutation frequency in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

Differentiation of metronidazole-sensitive and -resistant clinical isolates of Helicobacter pylori by immunoblotting with antisera to the RdxA protein

1 reference

https://api.crossref.org/works/10.1016%2FS0924-8579%2801%2900468-X

7 January 2021

10.1016/S0924-8579(01)00468-X

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11814762