(Q34510212)

2 August 2017

title

Ricin inhibits activation of the unfolded protein response by preventing splicing of the HAC1 mRNA. (English)

1 reference

2 August 2017

Bijal A Parikh

1

1 reference

2 August 2017

Andrew Tortora

series ordinal

2

1 reference

2 August 2017

Xiao-Ping Li

series ordinal

3

1 reference

2 August 2017

Nilgun E Tumer

series ordinal

4

1 reference

2 August 2017

language of work or name

English

0 references

publication date

7 January 2008

1 reference

Journal of Biological Chemistry

2 August 2017

published in

1 reference

2 August 2017

volume

283

1 reference

2 August 2017

issue

10

1 reference

2 August 2017

page(s)

6145-6153

1 reference

IRE1 signaling affects cell fate during the unfolded protein response

2 August 2017

cites work

1 reference

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Ribosome depurination is not sufficient for ricin-mediated cell death in Saccharomyces cerevisiae

7 July 2018

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7 July 2018

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Intracellular signaling by the unfolded protein response

7 July 2018

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7 July 2018

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7 July 2018

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Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

7 July 2018

1 reference

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Recognition and delivery of ERAD substrates to the proteasome and alternative paths for cell survival

7 July 2018

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EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol

7 July 2018

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Production of infectious human cytomegalovirus virions is inhibited by drugs that disrupt calcium homeostasis in the endoplasmic reticulum

7 July 2018

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Endoplasmic reticulum-associated degradation

7 July 2018

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ERAD: the long road to destruction

7 July 2018

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Human cytomegalovirus infection activates and regulates the unfolded protein response

7 July 2018

1 reference

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The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

7 July 2018

1 reference

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Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease

7 July 2018

1 reference

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Cytotoxic ribosome-inactivating lectins from plants

7 July 2018

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Pokeweed antiviral protein binds to the cap structure of eukaryotic mRNA and depurinates the mRNA downstream of the cap.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Retrograde transport of ricin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control

7 July 2018

1 reference

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

The pokeweed antiviral protein specifically inhibits Ty1-directed +1 ribosomal frameshifting and retrotransposition in Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Translational attenuation mediated by an mRNA intron

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Polynucleotide:adenosine glycosidase activity of ribosome-inactivating proteins: effect on DNA, RNA and poly(A).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Ricin: structure, mode of action, and some current applications.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024914

Evidence for retro-translocation of pokeweed antiviral protein from endoplasmic reticulum into cytosol and separation of its activity on ribosomes from its activity on capped RNA.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707981200

Pokeweed antiviral protein regulates the stability of its own mRNA by a mechanism that requires depurination but can be separated from depurination of the alpha-sarcin/ricin loop of rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707981200

Expression of a truncated form of ribosomal protein L3 confers resistance to pokeweed antiviral protein and the Fusarium mycotoxin deoxynivalenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707981200

Pokeweed antiviral protein inhibits brome mosaic virus replication in plant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707981200

Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18180297

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18180297

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M707981200

1 reference

2 August 2017

1 reference

2 August 2017

1 reference