(Q34515061)

PubMed publication ID

16624951

2 August 2017

title

Activated microglia contribute to the maintenance of chronic pain after spinal cord injury (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

0 references

0 references

Bryan C Hains

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

Stephen G Waxman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

1 April 2006

1 reference

PubMed publication ID

16624951

2 August 2017

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

page(s)

4308-4317

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids

11 May 2020

cites work

1 reference

12 December 2020

Differential activation of microglia after experimental spinal cord injury

1 reference

12 December 2020

Microglial reactions after subcutaneous formalin injection into the rat hind paw.

1 reference

12 December 2020

Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats: possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis

1 reference

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Involvement of primary afferent C-fibres in touch-evoked pain (allodynia) induced by prostaglandin E2

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12 December 2020

Chemical activation of cervical cell bodies: effects on responses to colorectal distension in lumbosacral spinal cord of rats

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12 December 2020

The efficacy of intrathecal morphine and clonidine in the treatment of pain after spinal cord injury

1 reference

12 December 2020

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

1 reference

12 December 2020

Neuropathic pain in aged rats: behavioral responses and astrocytic activation

1 reference

12 December 2020

Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398.

1 reference

12 December 2020

Glial activation: a driving force for pathological pain

1 reference

12 December 2020

Effects of IV morphine in central pain: a randomized placebo-controlled study

1 reference

12 December 2020

Spinal substance P release in vivo during the induction of long-term potentiation in dorsal horn neurons.

1 reference

12 December 2020

Efficacy of amitriptyline for relief of pain in spinal cord injury: results of a randomized controlled trial

1 reference

12 December 2020

Lamotrigine in spinal cord injury pain: a randomized controlled trial

1 reference

12 December 2020

P2X receptors in trigeminal subnucleus caudalis modulate central sensitization in trigeminal subnucleus oralis

1 reference

12 December 2020

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

1 reference

12 December 2020

Nerve root injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: considerations for persistent pain

1 reference

12 December 2020

Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury

1 reference

12 December 2020

Suppression of activated microglia promotes survival and function of transplanted oligodendroglial progenitors

1 reference

12 December 2020

Serotonin receptors 5-HT1A and 5-HT3 reduce hyperexcitability of dorsal horn neurons after chronic spinal cord hemisection injury in rat.

1 reference

12 December 2020

Serotonergic neural precursor cell grafts attenuate bilateral hyperexcitability of dorsal horn neurons after spinal hemisection in rat.

1 reference

12 December 2020

Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

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12 December 2020

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

1 reference

12 December 2020

Rats and mice exhibit distinct inflammatory reactions after spinal cord injury

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12 December 2020

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

1 reference

12 December 2020

Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia

1 reference

12 December 2020

Spinal substance p and N-methyl-d-aspartate receptors are coactivated in the induction of central sensitization of the nociceptive flexor reflex

1 reference

12 December 2020

Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes

1 reference

12 December 2020

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

1 reference

12 December 2020

A monitored contusion model of spinal cord injury in the rat

1 reference

12 December 2020

Upregulation of Sodium Channel Nav1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury

1 reference

12 December 2020

Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat.

1 reference

12 December 2020

Central sensitization and LTP: do pain and memory share similar mechanisms?

1 reference

12 December 2020

Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

1 reference

12 December 2020

Regeneration beyond the glial scar

1 reference

12 December 2020

Spinal cord injury pain--mechanisms and treatment

1 reference

12 December 2020

Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury

1 reference

12 December 2020

Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury.

1 reference

12 December 2020

Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury

1 reference

12 December 2020

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

1 reference

12 December 2020

Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain

1 reference

12 December 2020

Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis

1 reference

12 December 2020

Minocycline safety and tolerability in Huntington disease

1 reference

12 December 2020

Cell signaling and the genesis of neuropathic pain

1 reference

12 December 2020

Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats

1 reference

12 December 2020

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

1 reference

12 December 2020

The promise of minocycline in neurology.

1 reference

12 December 2020

Cell proliferation and replacement following contusive spinal cord injury

1 reference

12 December 2020

Immune and glial cell factors as pain mediators and modulators

1 reference

12 December 2020

Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation

1 reference

12 December 2020

Intravenous lidocaine relieves spinal cord injury pain: a randomized controlled trial

1 reference

12 December 2020

From discovery to clinical trials: treatment strategies for central neuropathic pain after spinal cord injury

1 reference

12 December 2020

Endogenous ATP involvement in mustard-oil-induced central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn).

1 reference

12 December 2020

Current status of clinical trials for acute spinal cord injury

1 reference

12 December 2020

Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury

1 reference

12 December 2020

Minocycline as a neuroprotective agent

1 reference

12 December 2020

Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury

1 reference

12 December 2020

Transcriptional profiling of spinal cord injury-induced central neuropathic pain

1 reference

12 December 2020

Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia

1 reference

12 December 2020

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury

1 reference

12 December 2020

Increases in the activated forms of ERK 1/2, p38 MAPK, and CREB are correlated with the expression of at-level mechanical allodynia following spinal cord injury.

1 reference

12 December 2020

Fire and phantoms after spinal cord injury: Na+ channels and central pain

1 reference

12 December 2020

Diagnostic spinal anaesthesia in chronic spinal cord injury pain

1 reference

12 December 2020

Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury.

1 reference

12 December 2020

Trazodone hydrochloride in the treatment of dysesthetic pain in traumatic myelopathy: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Efficient analysis of experimental observations.

1 reference

12 December 2020

A sensitive and reliable locomotor rating scale for open field testing in rats

1 reference

12 December 2020

Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists.

1 reference

12 December 2020

Quantitative assessment of tactile allodynia in the rat paw

1 reference

12 December 2020

Activated microglia are the principal glial source of thromboxane in the central nervous system

1 reference

12 December 2020

Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats

1 reference

12 December 2020

Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages

1 reference

12 December 2020

Chronic central pain after spinal cord injury

1 reference

12 December 2020

Characterization of variables defining hindpaw withdrawal latency evoked by radiant thermal stimuli.

1 reference

12 December 2020

Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior.

1 reference

12 December 2020

10.1523/JNEUROSCI.0003-06.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674010&resulttype=core&format=json

11 May 2020

PubMed publication ID

16624951

1 reference