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G protein-coupled estrogen receptor regulates mammary tumorigenesis and metastasis
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
title
G protein-coupled estrogen receptor regulates mammary tumorigenesis and metastasis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
main subject
G protein-coupled receptor
0 references
estrogen
1 reference
based on heuristic
inferred from title
author
Eric R Prossnitz
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
author name string
Nicole A Marjon
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Chelin Hu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Helen J Hathaway
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
publication date
16 July 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
published in
Molecular Cancer Research
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
volume
12
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
1644-1654
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
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PubMed Central
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GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts
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A novel estrogen receptor GPER mediates proliferation induced by 17β-estradiol and selective GPER agonist G-1 in estrogen receptor α (ERα)-negative ovarian cancer cells
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7 July 2018
The G protein-coupled estrogen receptor (GPER) is expressed in two different subcellular localizations reflecting distinct tumor properties in breast cancer
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PubMed Central
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7 July 2018
G protein-coupled estrogen receptor-selective ligands modulate endometrial tumor growth
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GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer
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7 July 2018
GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs).
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7 July 2018
G15, a GPR30 antagonist, induces apoptosis and autophagy in human oral squamous carcinoma cells
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7 July 2018
GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state
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PubMed Central
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7 July 2018
The novel estrogen receptor GPER regulates the migration and invasion of ovarian cancer cells
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PubMed Central
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7 July 2018
The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T-cell population under TH17-polarizing conditions
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PubMed Central
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7 July 2018
New insights into the mechanisms of organ-specific breast cancer metastasis
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7 July 2018
Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology
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PubMed Central
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7 July 2018
Alternate estrogen receptors promote invasion of inflammatory breast cancer cells via non-genomic signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Inactivation of GPR30 reduces growth of triple-negative breast cancer cells: possible application in targeted therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Cancer statistics, 2012
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
The G-protein-coupled estrogen receptor GPER in health and disease
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Hormone action in the mammary gland
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Estrogenic promotion of ErbB2 tyrosine kinase activity in mammary tumor cells requires activation of ErbB3 signaling.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Lessons in signaling and tumorigenesis from polyomavirus middle T antigen
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PubMed Central
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7 July 2018
Mechanisms of estrogen signaling and gene expression via GPR30
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PubMed Central
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7 July 2018
In vivo effects of a GPR30 antagonist
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30.
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PubMed Central
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7 July 2018
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
The effect of tamoxifen on the genital tract
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
GPR30 contributes to estrogen-induced thymic atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
7 July 2018
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Mouse models of breast cancer metastasis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Clinical characteristics of different histologic types of breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Prognostic and predictive factors in early-stage breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Estrogen receptor alpha in human breast cancer: occurrence and significance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Endocrine-responsive breast cancer and strategies for combating resistance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
7 July 2018
Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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7 July 2018
Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
7 July 2018
The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
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27 October 2018
G protein-coupled estrogen receptor: a new therapeutic target in stroke and traumatic brain/spinal cord injury?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
27 October 2018
Expression of CD133, PAX2, ESA, and GPR30 in invasive ductal breast carcinomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
27 October 2018
Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
27 October 2018
Virtual and biomolecular screening converge on a selective agonist for GPR30.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
27 October 2018
Estradiol promotes growth and angiogenesis in polyoma middle T transgenic mouse mammary tumor explants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233188
retrieved
27 October 2018
Lymph node ratio and breast cancer prognosis: a meta-analysis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25030371
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25030371
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The MMTV LTR promoter is induced by progesterone and dihydrotestosterone but not by estrogen
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25030371
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25030371
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1541-7786.MCR-14-0128-T
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PMC publication ID
4233188
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed publication ID
25030371
1 reference
stated in
Europe PubMed Central
PMC publication ID
4233188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25030371%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
ResearchGate publication ID
264008207
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