(Q34522629)

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Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice.

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scholarly article

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6 February 2020

Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice (English)

1 reference

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6 February 2020

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6 February 2020

author name string

Andrea L Clark

1

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6 February 2020

Bartholomew J Votta

2

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6 February 2020

Sanjay Kumar

3

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6 February 2020

Wolfgang Liedtke

4

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6 February 2020

publication date

1 October 2010

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6 February 2020

Arthritis and Rheumatism

1 reference

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6 February 2020

62

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6 February 2020

2973-2983

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6 February 2020

10

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Europe PubMed Central

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6 February 2020

Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

The progesterone receptor regulates the expression of TRPV4 channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Transient receptor potential vanilloid 4 deficiency suppresses unloading-induced bone loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Joint degeneration following closed intraarticular fracture in the mouse knee: a model of posttraumatic arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Osteoarthritis severity is sex dependent in a surgical mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Dynamic expression of the osmosensory channel trpv4 in multiple developing organs in zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Transient receptor potential vanilloid 4 regulates aquaporin-5 abundance under hypotonic conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

The role of mechanical loading in the onset and progression of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

TRP channels: a TR(I)P through a world of multifunctional cation channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

TRPV4 plays an evolutionary conserved role in the transduction of osmotic and mechanical stimuli in live animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

TRPV4 as osmosensor: a transgenic approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Dynamic osmotic loading of chondrocytes using a novel microfluidic device.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Abnormal osmotic regulation in trpv4 -/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

The TRPV4 channel: structure-function relationship and promiscuous gating behaviour.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Hypo-osmotic stress induces calcium-dependent actin reorganization in articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

A family of calcium-permeable channels in the kidney: distinct roles in renal calcium handling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Hyper-osmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

The osmotic sensitivity of isolated and in situ bovine articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Regulatory volume decrease (RVD) by isolated and in situ bovine articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Calcium as a versatile second messenger in the control of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

The extracellular matrix, interstitial fluid and ions as a mechanical signal transducer in articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Ratiometric confocal Ca(2+)-measurements with visible wavelength indicators in isolated cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

Calcium signaling in cell volume regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

7 July 2018

TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

Epidemiology of osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

Chondrocyte intracellular calcium, cytoskeletal organization, and gene expression responses to dynamic osmotic loading.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

A mechano-chemical model for the passive swelling response of an isolated chondron under osmotic loading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

Mechanisms involved in the increase in intracellular calcium following hypotonic shock in bovine articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

Changes in intracellular calcium concentration in response to hypertonicity in bovine articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

Effects of cell swelling on intracellular calcium and membrane currents in bovine articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

Diurnal variation in the femoral articular cartilage of the knee in young adult humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

27 October 2018

A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027356

9 December 2018

Adaptive cellular response to osmotic stress in pig articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disparate aggrecan gene expression in chondrocytes subjected to hypotonic and hypertonic loading in 2D and 3D culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural history of degenerative joint disease in small laboratory animals. II. Epiphyseal maturation and osteoarthritis of the knee of mice of inbred strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory volume increase (RVI) by in situ and isolated bovine articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of osteoarthritis by intra-articular injection of collagenase in mice. Strain and sex related differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthrosis and osteoporosis in senile mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Na+, K+-ATPase density by the extracellular ionic and osmotic environment in bovine articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of osmotic and mechanical pressures on water partitioning in articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biomechanical role of the chondrocyte pericellular matrix in articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20583100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.27624

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20583100%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20583100%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20583100%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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